Show:
Flash
Boss Rush Wiki Edition
Character Unlocks
Item Subtext
Unlock Requirement
100

What year was Isaac released on steam?

When is 2011

100
  • Hops towards Isaac.
  • Coughs up a large number of disorganized projectiles towards Isaac.
  • Jumps off-screen, aiming to land on top of Isaac. Create a burst of disorganized projectiles in all directions on landing.

Who is Monstro?

100

Azazel Kills Blue Baby/???

What is Abaddon?

100

Reroll your destiny

What is The D6

100

Blood Bag

What is using a Blood Donation Machine 30 times?

200

What character released with the Wrath of the Lamb DLC?

Who is Samson?

200

Quickly fires 

  • Brimstone laser towards Isaac if he is seen in any cardinal direction. The beam bends slightly, following Isaac's movement.
  • Flies off-screen into the air and plummets down on Isaac's position a few seconds later, creating a circular rock wave on impact which expands to 4 rings.
  • Summons 3  
  • Spiders.
  • Dims the room, causing the Curse of  Darkness effect for a period of time. 

Who is "The Adversary"

200

Isaac Kills The Lamb

What is the "Missing Poster"

200

"She Loves You"

SISSY!
What/Who is Sissy Longlegs.

200

Counterfeit Penny

What is playing the shell beggar 100 times?

300

The Original Name of the D6

What is "The Dice"
300
  • Creates temporary spikes in the boss room in random locations.
    • These spikes can spawn under Isaac but have a small delay before they can deal damage.
  • Spews a volley of large orange projectiles towards the bottom of the room, leaving slowing Orange Creep.
  • Shoots 3, 4, or 7 waves of 5 spread projectiles at Isaac's location.
  • Shoots a burst of disorganized projectiles at Isaac.
  • Occasionally retreats upwards off-screen before executing her spike attack. Performs its orange projectile attack immediately upon re-entering the screen.

Who is "Mama Gurdy"

300

The Keeper kills Delirium

What is "Crooked Penny"

300

Swing It

What is Guppy's Hairball?

300

A Bandage

What is picking up Ball of Bandages 4 times?

400

DAILY DOUBLE!!!!
What is the total amount of items in flash isaac (Including wrath of the lamb update)?

(Buffer Area of 5)

What is 198?

400
  • Burrows underground, then quickly reemerges elsewhere in the room and fires 5 bone projectiles in a spread towards Isaac. The Boss repeats this attack 3 times in a quick succession. It will generally try to reemerge close to Isaac or directly in his path to cut him off.
  • Summons a Bony with a maximum of 2 alive at once.
  • Summons spikes in each of its cardinal directions which start at the edges of the room and move towards the Boss.
  • Charges in Isaac's direction and continues until it rams into a wall or an obstacle, creating two diagonal lines of rock waves away from the wall and launching a spray of bone projectiles in Isaac's direction. If it runs into an obstacle it also destroys it along with any other obstacles in a small radius. 

Who is "The Pile"

400

Defeat Hush as Jacob and Esau.

What is Vanishing Twin?

400

May You Get What You Came For

What is The Stairway

400
Lil Spewer

What is "Die to your own Ipecac Explosion"

500

The Unlock Requirement for Samson

Skipping two treasure rooms and defeating mom in the same run.

500

Shoots a large, fast cluster projectile out of its hood that homes in slightly on Isaac. When it hits a wall, it explodes into a spray of projectiles, leaving behind damaging Green Creep and a cluster of Small Maggots.

  • If The Boss is below half health, it instead shoots out three slower, smaller cluster projectiles from out of its hood that create fewer projectiles on impact.
  • Launches one of its tendrils towards Isaac and embeds it in a wall. It then drags the tendril along the wall, causing projectiles, creep, and Small Maggots to shoot out from the wall.
  • Launches two tendrils and embeds them into the wall, one directly at Isaac and one in the cardinal/ordinal direction opposite of him. It then starts rotating its arms around while shooting two rings of 12 projectiles outwards.
  • Launches two tendrils to either side of Isaac, embedding them into the wall and trapping him in a triangle-shaped area. It will then perform one of two attacks:
    • Fires walls of tight projectiles with gaps to pass through from its body. It follows up each wave with an additional, faster projectile aimed directly at Isaac.
    • Fires horizontally traveling projectiles randomly out from both its left and right tendrils.
    • If Isaac gets caught out of this triangle space for any reason, The Boss will cancel this attack.
      • The three previous attacks end if The Boss or its tendrils take enough damage. Each tendril has a total HP of 400.
      • The Boss takes damage equal to 25% of the damage its tendrils take.
      • The tendrils passively take heavy damage if they're dragged along a wall, dealing a total of 50 damage to The Boss for each tendril dragged.
      • The tendrils kill Small Maggots they are dragged into.
  • Moves to the center of the room and begins sucking in 2 tight streams of projectiles towards it in a spiral pattern. This spiral pattern can randomly switch directions during the attack. Additional random projectiles can appear in the gap between the two streams, further limiting the space.

Who is "The Scourage"

500

Defeat Mega Satan as Tainted Jacob

What is/are Golden Trinket(s)?

500

"It Feels Cursed"

What is the Broken Shovel

500

Angry Fly

What is "Transforming Into Beelzebub"