Localization - The Eyes
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Localization - Brainstem ;\
Localization - Peripheral {=
Localization - Cortical @
Localization - Wild Card
100

A patient with a seizure arising from the right frontal lobe is most likely to have this ocular finding during the seizure event

What is a forced gaze deviation to the left? 

100

A patient presenting with left arm and leg weakness and upper motor neuron signs due to a pontine stroke is most likely to have a lesion in this specific region

What is the right basis pontis?

100

A patient with atrophy of the hypothenar eminence in the right hand is likely to have sensory loss in this distribution

What is the palmar surface of the medial 1.5 digits (5th and medial half of 4th)

100

A patient with extinction to dual simultaneous stimulation on the left is likely to have a lesion in this lobe of the brain

What is the right parietal lobe?

100
A patient presenting with reduced vision in the peripheral fields of both eyes likely has a compressive lesion affecting this brain structure

What is the optic chiasm? 

200

A patient presenting with a right homonymous inferior quadrantanopia is most likely to have a lesion in this lobe of the brain

What is the left parietal lobe?

200

A 48-year-old comatose man with intact pupillary and corneal responses, and absent bilateral gag reflex is most likely to have a lesion in this portion of the brainstem

What is the medulla?

200

A patient presenting with hip abductor and dorsiflexion weakness (foot drop) with normal reflexes is most likely to have a lesion of this lumbosacral nerve root

What is L5?

200

A border zone infarct involving the left ACA-MCA watershed zone is most likely to cause difficulties with these primary language functions

What are fluency +/- naming (sparing comprehension and fluency)? 

200

A patient presenting with right arm and leg weakness and deviation of the tongue to the left is most likely to have a lesion in this region of the nervous system

What is the left medulla? 

300

A patient with anisocoria that is most prominent in dim light is likely to have this additional ocular symptom

What is ptosis? 

300

A stroke involving the right medial lemniscus has interrupted fibers that are destined for this nucleus

What is the right VPL nucleus of the thalamus

300

A patient who undergoes treatment with botulinum toxin has weakness in the injected muscle due to interference with this step in neuromuscular junction transmission

What is vesicular release?

300

A patient with a large left posterior cerebral artery stroke is most likely to have this language deficit in addition to an associated right homonymous hemianopia

What is alexia without agraphia? 

300

A patient presenting with transverse myelitis affecting the right side of the spinal cord at T10 is most likely to have loss of these sensory modalities in the right leg

What is vibration and proprioception (epicritic)?

400

A patient presenting with left-sided weakness of the entire face as well as an inability to abduct the left eye is most likely to have a lesion in this specific region of the pons

What is the facial colliculus?

400

A 76-year-old woman presenting with a new onset clicking sensation in her ear, and an observed palatal tremor on examination is likely to have a lesion causing disconnection between these three nuclei

What are the dentate, red, and inferior olivary nuclei?

400
A patient presenting with slowly progressive ophthalmoparesis, pigmentary retinopathy, and cardiac conduction defects is most likely to have this pathological finding on muscle biopsy

What are ragged red fibers? 

400

A patient presenting with truncal ataxia is most likely to have a lesion to cerebellar cortex fibers destined for this deep cerebellar nucleus

What is the dentate nucleus? 

400

A patient presenting with left-sided weakness, right-sided ptosis, and anisocoria that resolves in a bright room or with pupillary light reflex testing should raise concern for this stroke mechanism

What is a (right) carotid dissection? [also acceptable: atheroembolism]

500

A patient presenting with an inability to initiate upgaze is most likely to have a lesion involving this specific brain region

What is the pretectum? 

500

A 51-year-old man presenting with right-sided ataxia, loss of pinprick sensation on the right face, and loss of pinprick sensation in the left arm and leg is most likely have this associated eye finding

What is a right Horner's syndrome? (also acceptable right ptosis and miosis)

500
A patient presenting with weakness in the deltoid, biceps, and brachioradialis, absent biceps and brachioradialis reflexes, and reduced sensation in the lateral arm, forearm, and thumb most likely has a lesion here

What is the upper trunk of the brachial plexus? 

500

Balint syndrome, secondary to bilateral parieto-occipital lesions is characterized by this clinical triad

What is optic ataxia, oculomotor apraxia, and simultagnosia

500
A patient presenting with acute angle closure glaucoma is likely to have a blockage of this outflow pathway for aqueous humor

What is the Canal of Schlemm?