Holo It's Me, A Murmur!
Go Big or Go Home
Unbreak My Heart
Heart-Shaped Box
100

The murmur of this valvular condition is heard best along the left sternal border 3-4th intercostal space with the patient sitting upright and leaning forward with breath held after exhalation.

What is aortic insufficiency?

100

Functional dilation of the mitral valve occurs predominantly at this location of the annulus

What is the posterior leaflet?

100

This drug, used to treat heart failure with reduced ejection fraction,substantially reduces mortality and has a number needed to treatof just 9 over 2 year follow up!

What is spironolactone. 


In the RALES trial, over a median follow up of 24 months, mortality was 35% in the spironolactonegroup vs 46% in theplacebo group.

100

This common congenital finding is typically asymptomatic, but maybe associated with ischemic symptoms.

What is myocardial bridging?

200

The intensity of the murmur associated with Hypertrophic Cardiomyopathy does this with a Valsava manuever.

What is increases?

200

The aortic sinus most likely to be involved in sinus of valsalva aneurysm.

What is the right coronary sinus?

200

In primary mitral regurgitation, either of these two ECHO findings warrant mitral valve surgery regardless of symptoms.

What is an LVEF ≤60% or End Systolic Dimension ≥40 mm?

200

The serious complication of the congenital heart surgery shown here includes symptoms of diarrhea, ascites, and fever.


What is protein-losing enteropathy?

The causes are not well understood, but likely include a combination of lymphatic insufficiency, high central venous pressure, loss of heparan sulfate from intestinal epithelial cells, abnormal mesenteric circulation, and intestinal inflammation

300

The change in the mid-diastolic murmur of tricuspid stenosis with inspiration.

Bonus points: What is the name of the sign?

Increase in intensity; Carvallo's sign.

300

The most common contraindication to deploy a percutaneous bioprosthetic pulmonary valve.

What is coronary compression?

300

When evaluating for the presence of Stage D3 symptomatic severelow-gradient aortic stenosis with normal LVEF, careful attention must be made to ensure this hemodynamic parameter is met when obtaining measurements.

What is a systolic blood pressure < 140 mmHg?

300

The most common surgically significant coronary anomaly seenhere in Tetralogy of Fallot patients, occurring in 4-7% of patients.

What is anomalous origin of the LAD from the RCA?  The course of ther artery puts it at risk during standard ventriculotomy, as the LAD crosses over the RVOT.

400

The condition associated with a "machine-like" murmur.

What is a patent ductus arteriosus?

400

According to STS Guidelines, surgical ablation for symptomatic AF by pulmonary vein isolation alone is not recommended when left atrial enlargement is this size or greater.  

What is 4.5 cm?

400

What is cardiac myosin inhibition?


Reduces excess actin–myosin cross-bridging by decreasing myosin adenosine triphosphatase activity of the cardiac myosin heavy chain, which results in decreased sarcomere power and force generation, or decreased contractility.

400

What is the nodule of Arantius?

500

This congenital heart defect commonly develops a diastolic rumble on cardiac auscultation

What is an atrial septal defect?

500

In patients with HOCM, the Brckenbrough phenomenon describes this response to a PVC.  

What is a paradoxical decrease in arterial pulse pressure after a PVC.

500

CABG plus optimal medical therapy was shown in a randomized trial to provide better 10-year survival in ischemic cardiomyopathy and reduced EF than medical therapy alone. 

A more recent trial investigating whether revascularization by PIC could improve event free survival and LVEF in patients with severe ischemic LV systolic dysfunction compared with medical therapy alone did not show any benefit of PCI.

These are the two trials described above.

What are the STICH and REVIVED-BCIS2 Trials?

STICH

1212 patients with CAD and EF <35% randomized to CABG or Medical Therapy

REVIVED BCIS2 trial
•347 PCI grp, 353 OMT

•Primary outcome death from any cause or hospitalization for HF

500

The eponymous name for the abnormality shown here:

What is Yamaguchi Syndrome?