Jeopardy!

Down Syndrome

100

True or False: Down Syndrome can affect anyone regardless of gender

True! Down Syndrome is a genetic mutation.

200

Down syndrome occurs when an individual has a full or partial extra copy of which chromosome?

Chromosome 21 

300

True or False: There are different types of Down syndrome.

True! 

400

What percentage of all cases of Down syndrome have a hereditary component (passed from parent to child through the genes)?

1%

Ethics

100

This ethical principle involves supporting pregnant individuals’ choices, whether it involves pursuing or declining prenatal testing for Down syndrome.

Respect to autonomy

200

Offering prenatal testing for Down syndrome at no cost has led to a significant reduction in the number of individuals with Down syndrome. This community is impacted in terms of visibility, representation, and support.

Down syndrome community

300

This ethical consideration applies to perspectives in Nordic countries where abortions after Down syndrome diagnosis on a prenatal screening is normal.

Respect for cultural and ethical values

400

Personal contact with disabled people is associated with more positive attitudes towards disability, which in turn are associated with less favourable attitudes to termination of affected pregnancies; over time, a significant reduction in the number of people with Down syndrome would reduce opportunities for personal interaction. Name one ethical principle that may be considered.

Autonomy, Beneficence, Non-discrimination/Respect for Diversity, Justice and fairness, Respect for human dignity, Long-term Societal Impact

Nordics

100

True or False: Denmark was the first country in the world to implement a national, free-for-all offer of prenatal screening for Down syndrome to all pregnant women.

True!

200

Which country has the highest Down syndrome elimination rate?

Iceland

300

Around how many babies with Down syndrome are born each year in Iceland?

1 to 2 babies

400

What is Iceland’s termination rate after pre-natal screening for Down Syndrome?

100% 

Prenatal Testing

100

This type of test can identify individuals at increased risk of having a baby with Down syndrome.

Screening test

200

What are the two categories of tests for Down syndrome that can be performed before a baby is born?

Screening and diagnostic tests 

300

How accurate is the screening test? (%)

85%

400

Amniocentesis is taken place for a diagnostic test. During amniocentesis, a sample of amniotic fluid is taken from around the baby and the test is usually done at 15 to 20 weeks. Although not perfect, it is very accurate in diagnosis. Some women may not want to do this invasive procedure due to what risk?

Miscarriage