Microbiome Methods
This technology was used to analyze microbial signatures in the study.
What is 16S rRNA sequencing?
This IBD subtype demonstrates lower microbial diversity and a more altered microbiome composition.
What is Crohn’s Disease?
These are the groups of patients studied and compared.
What are patients with CD, UC, healthy controls, and patients with IBS or anorexia?
These were the differences seen between smokers and non-smokers in the microbial composition of CD and UC patients.
What are differences in relative abundance of specific bacterial genera?
These two bacterial genera were increased in Crohn’s patients and helped distinguish them from other groups.
What are Fusobacterium and Escherichia?
This region was amplified by PCR to profile microbiome composition.
What is the V4 region?
Patients with this disease showed lower richness and lower evenness compared to healthy controls and UC patients.
What is Crohn’s Disease?
These are the time intervals in which microbiome stability was measured.
What are 3-month intervals?
In Crohn’s Disease patients, this bacterial family was more abundant in smokers, while Eggerthella lenta was more abundant in non-smokers.
What is Peptostreptococcaceae?
These beneficial bacteria were found in lower abundance in Crohn’s patients and are known for producing butyrate.
What are Faecalibacterium, Christensenellaceae, Methanobrevibacter, and Anaerostipes?