The Brain
You Know
Me
Change my Mind
Good Chemicals

Hormones that Change Your Mood
100

This brain structure connects emotion to memory and plays a major role in craving and relapse.

What is the amygdala?

100

After surviving child abuse and poverty, she became one of the most influential talk show hosts and philanthropists in the "world". 

Who is Oprah Winfrey?

100

Doing this simple act for ten minutes a day can quiet your mind, reduce anxiety, and strengthen focus — no app required.

What is meditation?


100

Often called the “feel-good hormone,” this neurotransmitter is linked to pleasure, motivation, and reward — it spikes when you achieve a goal or enjoy a treat.

What is dopamine?


100

Known as the body’s natural painkiller, this group of hormones is released during exercise, laughter, or excitement, often producing a “runner’s high.”

What are endorphins?

200

The brain region that helps form new memories — and often shrinks from long-term drug or alcohol abuse.

What is the hippocampus?


200

This British singer overcame heroin addiction an an eating disorder before becoming one of the best-selling female artists of all time.

Who is Elton John?

200

Doing this kind of physical activity releases endorphins, improves mood, and boosts creativity — even a brisk walk can do it.

→ What is exercise?


200

This process allows the body to repair and restore itself every night.

What is sleep?

200

This mood-related hormone is produced in the pineal gland and helps regulate your sleep cycle.

What is melatonin?


300

This “CEO of the brain” helps you make decisions and control impulses — but drugs can weaken its function.

What is the prefrontal cortex?


300

After surviving domestic violence, she wrote the chart-topping anthem "Stronger (What Doesn't Kill you)".

Who is Kelly Clarkson?

300

By questioning automatic negative thoughts and reframing them, you practice this powerful cognitive skill at the core of therapy and self-awareness.

What is cognitive reframing (or cognitive restructuring)?

300

Known as the “love hormone,” this chemical strengthens bonds between people and is released during hugging, childbirth, and even petting animals.

What is oxytocin?


300

Though known as the “male hormone,” this one influences energy, confidence, and motivation in all genders.

What is testosterone?


400

This term describes the brain’s ability to change and rewire itself based on experiences.

What is neuroplasticity?

400

This South African leader survived 27years in prison before leading his nation to democracy.

Who is Nelson Mandela?

400

Turning your mistakes into learning opportunities helps strengthen neural pathways for adaptability and resilience — a process sometimes called this.

What is neuroplasticity (or building neural resilience)?

400

This hormone stabilizes mood and contributes to feelings of well-being and happiness; many antidepressants work by increasing its levels.

What is serotonin?


400

When this thyroid hormone is out of balance, it can cause fatigue, anxiety, or depression, showing how strongly metabolism links to mood.

What is thyroxine (T4)

500

Repeated drug use can “rewire” this executive area of the brain, making self-control much harder over time.

What is the prefrontal cortex?

500

After nearly dying from an overdose,  this Jackass star wet to rehab and became a vocal advocate for recovery.

Who is Steve O?

500

Writing down three good things that happened each day helps train your brain to focus on positives instead of problems.

What is practicing gratitude journaling?


500

Released during stress, this hormone helps your body respond to danger — but too much of it over time can lead to anxiety or burnout.

What is cortisol?


500

This desire to please others can build harmony, but may also lead to self-neglect or resentment.

What is people-pleasing?