Prefix
Suffix
Define-prefix
Numbers
Define-suffix
1

anti

against

1

-er

someone who performs an action

1

inactive

not involving activity

1

uni

1

1

argument

a dissagreement 

2

hyper

above/a lot

2

-ness

the state of being

2

disadvantage

a circumstance that reduces the chance of success 

2

penta

5

2

rudeness 

the state of being rude
3

poly

many

3
-ship

position held

3

semiannual 

twice a year 
3

centi

100

3

fellowship 

friendly association

4

scler(o)

hard

4

-ity

state or condition of

4

prologue

a separate introductory piece of literature

4

ennea

9

4

endorsement

public approval