Pleural Effusion
Pathogenesis/Tx of PNA
Complications of PNA
Hypoxemia/Hypercapnia/acid-base
100

The type of effusion that is thick, proteinaceous, and cellular is called 

What is exudative effusions 

100

Risk factors for pneumonia include (at least 3)

What are aspiration of food, bronchiectasis, being immunocompromised, recent travel. lung disease, and smoking history?

100

Pulmonary vascular resistance increases due to 

What is hypoxia? 


(hypoxia causes hypoxic pulmonary vasoconstriction to shunt blood away from poorly ventilated areas)

100

Hypercapnia causes respiratory 

What is acidosis?


(CO2 reacts with water to form carbonic acid (H2CO3), which then dissociates into bicarbonate (HCO3–) and hydrogen (H+) ions)

200

Pleural effusion due to pneumonia is caused by 

What is capillary inflammation?

200

Pneumonia overcomes immune defense mechanisms like (at least 2)

What are mucociliary clearance, cough reflex, and alveolar macrophages?

200

Pulmonary hypertension can cause 

What is cor pulmonale? 

(right ventricle now has to pump against higher pressure -> acute strain or failure of the right ventricle = cor pulmonale)

200

The body is better at tolerating (hypoxia or hypercapnia)

What is hypercapnia?

300

The procedure done to determine the cause of the pleural effusion is called 

What is thoracentesis (pleural tap) 

300

Hypoxemia develops as a result of pneumonia due to 

What is impaired gas exchange? 

(alveoli become filled with exudate, fibrin, neutrophils, and bacteria)

300

Clinical manifestations of RHF include: (at least 3) 

What is jugular venous distension, hepatomegaly, peripheral edema?

300

Pneumonia can cause hypercapnia by 

What is ventilation/perfusion (V̇/Q̇) mismatching?


(increased pathologic dead space due to fluid entering the alveoli -> Gas exchange drops, and the CO2 starts to build up in the alveolus and the blood)

400

Pleural effusion is excess accumulation of pleural fluid greater than _______ mL 

What is 15 mL?

400

The main treatment protocol for pneumonia is 

What is amoxicillin + a macrolide?

400

Respiratory distress due to pneumonia manifests as: (at least 2)

What is ↑ heart rate, ↑ respiratory rate, use of accessory muscles, cyanosis, and confusion. 

400

Increased PaCO2 triggers chemoreceptors in the 

What is medulla and periphery (aortic arch and carotid arteries)? 

500

The main three factors measured in thoracentesis (pleural tap) are: 

What is pleural serum/protein ratio, pleural/serum lactate dehydrogenase ratio, and pleural lactate dehydrogenase


exudate needs 1 met: 1) >.5, 2) >.6, and 3) > 200 mL

500
One pneumonia is diagnosed, patients are automatically given

What are empiric antibiotics (ex. ceftriaxone)? 

500

A complicated effusion is an effusion that contains 

What is bacteria? 

(Our patient had a negative gram stain so NOT a complicated effusoin)

500

The main compensation mechanisms for metabolic acidosis are: 

What is increased minute ventilation and renal bicarbonate retention?