Radiation Biology
This unit measures absorbed radiation dose and replaced the rad in the SI system
What is the Gray (Gy)
This enzyme converts Angiotensin I into Angiotensin II
What is ACE (angiotensin-converting enzyme)
This stain is commonly used to visualize collagen deposition in fibrotic tissue
What is Masson's Trichrome
This method of delivering compounds directly into the stomach is commonly used in rodent studies
What is oral gavage
You planned to add 10 µL to a tube but accidentally ejected the entire pipette tip contents onto the bench
What is “I guess we’re starting that experiment over”
This principle minimizes radiation exposure by keeping doses ALARA. What does ALARA stand for?
As Low As Reasonably Achievable
This small molecule ACE2 activator has been shown to improve survival following radiation exposure in rodent models
What is Diminazene Aceturate (DIZE)
This radiation syndrome is caused by severe damage to bone marrow
What is the hematopoietic syndrome
This model irradiates the body while shielding specific organs such as bone marrow to study GI injury
What is partial body irradiation
Your western blot bands look perfect. That is, until you realize the samples were loaded in the wrong order.
What is “label your tubes better next time”
These are packets of electromagnetic energy commonly used in medical radiation therapy
What are X-rays
ACE2 expression is particularly high in these two organ systems relevant to radiation injury
What are the lungs and gastrointestinal tract (small intestine)
Radiation injury that occurs within days to weeks after exposure is called this
What is an acute radiation syndrome
The standard method used to quantify fluorescence intensity from plasma samples in permeability assays
Hint: Unit it's recorded as or technique is accepted
What is fluorescence (RFU)
or
What is plate reader fluorescence measurement (RFU)
A new piece of equipment has been delivered, what is always the first responsibility before use?
What is giving it a name
Radiation that has enough energy to remove electrons from atoms is called this type of radiation
What is ionizing radiation
ACE2 cleaves Angiotensin II to generate this heptapeptide
What is Angiotensin-(1–7)
DAILY DOUBLE
In Masson's Trichrome staining, collagen fibers are typically visualized in this color
What is blue
DAILY DOUBLE
The most common response when a grad student hears “just one more experiment.”
What is panic
Someone just finished reorganizing the shelves and benchtops in 4072. They quickly use the bathroom, and when they come back, the space is in disarray. What storm system likely caused this destruction?
Hurricane Anne
This type of radiation transfers energy densely along its path and often causes complex DNA damage
What is High-LET (Linear Energy Transfer) radiation
DAILY DOUBLE
Angiotensin-(1–7) signaling through Mas receptor promotes this endothelial signaling molecule responsible for vasodilation.
What is nitric oxide (NO)
This epithelial marker indicates cellular proliferation during tissue regeneration
Hint: cells of interest show up brown
What is Ki-67
The statistical test commonly used to compare multiple treatment groups across time
What is two-way ANOVA
This mysterious lab phenomenon occurs when an experiment works perfectly for the PI but never again for anyone else
What is “PI magic”