CRMY
This is CRMY’s bold vision for the future of cancer.
What is a future free of the fear of cancer?
Walt Disney made history with this 1937 release — his studio’s first full-length animated film
What is "Snow White and the Seven Dwarfs"?
The original conceptual model includes:
1. Sustaining proliferative signaling
2. Evading growth suppressors
3. Resisting cell death (apoptosis)
4. Enabling replicative immortality
5. Inducing angiogenesis
6. Activating invasion and metastasis
What is the "Hallmarks of Cancer"?
She won the Best Actress Oscar in 2023 for her role in Everything Everywhere All at Once, becoming the first Asian woman to receive the honor.
Who is "Michelle Yeoh"?
The de-methylation of this genomic element can lead to oncogene overexpression by acting as a cryptic promoter.
What is a "transposable element"?
From:
Educational Program: Transposable Elements in Cancer: Contributions to Tumor Biology and Novel Therapeutic Targets
This digital tool marks Malaysia’s first mobile approach to early oral cancer detection.
What is "MeMoSa"?
Famous movie quote:
“Bond. James Bond.”
What is the famous quote out of the movie "Dr. No (1962)"?
Inherited mutations in these two genes significantly raise the risk of developing breast and ovarian cancer.
What are "BRCA1 and BRCA2"?
In 1998, malaysia became the first country in the world to issue this, which contains an embedded chip storing the holder’s personal and biometric data.
What is the "biometric passport"?
This concept aims to ensure all individual has a fair and just opportunity to be as healthy as possible; requires removing obstacles and eliminating health disparities and determinants that adversely affect excluded or marginalized groups.
What is "Health Equity"?
From:
Plenaries: Bridging the Gap: Ensuring a Broad Representation of Patients in Cancer Clinical Trials
IN 2024: KOTA BHARU, KUALA LUMPUR, IPOH AND SUNGAI PETANI
IN 2025: MoU signed in KK
-name of the centre-
What is the "Pink Ribbon Centre"?
#ExplainAFilmPlotBadly
-NO QUESTION AS ANSWER-
EVERYONE TRIES THE ICE BUCKET CHALLENGE
Titanic (1997)
Disruption of [THIS CYCLE] can trigger epigenetic modifications across tissues, leading to remote, cross-tissue interactions that disrupt normal tissue-specific functions.
What is the "circadian rhythm"?
This zoonotic virus was first identified in 1999 among pig farmers in Malaysia and named after the village where the first cases occurred.
What is the "Nipah virus"?
This oncogene was considered 'undruggable' due to its smooth structure and lack of obvious binding pockets, despite being the first oncogene to be discovered (1983).
What is "K-Ras"?
From:
Opening Plenary: Unifying Cancer Science and Medicine—A Continuum of Innovation for Impact
(this session update on how different compounds were experimented to target the most common mutation in K-Ras)
Aiming to improve access to precision medicine, this CRMY study delivers genetic counselling and BRCA testing to ovarian cancer patients across Malaysia, regardless of where they live.
What is the "MaGiC study"?
#ExplainAFilmPlotBadly
-NO QUESTION AS ANSWER-
GIRL WAKES UP TO A STRANGER ON TOP OF HER IN BED, BUT IT‘S COOL CAUSE HE‘S HOT.
The Sleeping Beauty (1959)
These circular DNA fragments, found only in cancer cells, often carry multiple copies of oncogenes and are a major driver of tumor evolution.
What is the "extrachromosomal DNA (ecDNA)?"
This patented reinforced-soil retaining wall system, invented by a Malaysian engineer and used worldwide for highways and infrastructure, is named after a biblical figure.
What is the "Nehemiah wall"?
In his presentation, Prof. Douglas Hanahan described this phenomenon, in which tumors release IL-1 family cytokines into circulation, reprogramming bone marrow and lymphoid organs to expand immunosuppressive neutrophils—thereby impairing T cell–mediated antitumor immunity throughout the body.
What is "systemic immunosuppression"?
From:
Lectures: Pezcoller Foundation-AACR International Award for Extraordinary Achievement in Cancer Research
A true symbol of strength and resilience, this cancer survivor pushes physical limits by running ultramarathons to raise both funds and awareness for CRMY’s campaign.
Who is "Frank Chong"?
This beloved film introduced the world to 'Somewhere Over the Rainbow' as its very first song.
What is "The Wizard of Oz (1939)"?
This effect, named after a German biochemist, describes how cancer cells preferentially use glycolysis for energy production even when oxygen is abundant.
What is the "Warburg effect"?
Often called the "Lost World of Sabah," this circular rainforest basin is so untouched that large parts of it remain unexplored, and it may have formed from a meteor impact.
What is the "Maliau Basin"?
This approach replaces random self-organization with geometric templates, using scaffolds to control organoid shape and cell fate patterning, enabling the creation of long-lived, perfusable mini-intestines
What is "scaffold-guided organoid morphogenesis"?
From:
Plenaries: Innovative Technologies Driving Advances in Cancer Research