CEQUA
AAOpt
DED
Disneyland
100

CEQUA uses this proprietary delivery platform, designed to improve penetration of cyclosporine into ocular tissues.

What is NCELL® technology?

100

This four-letter designation identifies fellows of the American Academy of Optometry.

What is FAAO?

100

Symptoms of Dry Eye Disease can include burning, stinging, blurry vision, and this common sensation.

What is a feeling of grittiness or having something in the eye?

100

This television network helped finance Disneyland in exchange for a weekly Disney TV program.

What is ABC?

200

CEQUA Phase 4 data presented at AAOPT 2023 showed significant improvements in dry eye signs and symptoms in patients switched from this cyclosporine product.

What is Restasis®?

200

The American Academy of Optometry was founded in this year.

What is 1922?

200

This oil-producing gland in the eyelid helps prevent tears from evaporating too quickly.

What are the Meibomian glands?

200

This iconic Disneyland structure located at the end of Main Street, U.S.A., serves as the symbol of the park.

What is Sleeping Beauty Castle?

300

Unlike artificial tears that primarily provide lubrication, CEQUA targets this underlying driver of dry eye disease to help increase natural tear production.

What is ocular inflammation?

Indications and Usage

CEQUA (cyclosporine ophthalmic solution) 0.09% is a calcineurin inhibitor immunosuppressant indicated to increase tear production in patients with keratoconjunctivitis sicca (dry eye).

Important Safety Information

CONTRAINDICATIONS

None.

WARNINGS AND PRECAUTIONS

Potential for Eye Injury and Contamination: To avoid the potential for eye injury and contamination, advise patients not to touch the vial tip to the eye or other surfaces.

Use with Contact Lenses: CEQUA should not be administered while wearing contact lenses. If contact lenses are worn, they should be removed prior to administration of the solution. Lenses may be reinserted 15 minutes following administration of CEQUA ophthalmic solution.

Adverse Reactions

The most common adverse reactions reported in greater than 5% of patients were pain on instillation of drops (22%) and conjunctival hyperemia (6%). Other adverse reactions reported in 1% to 5% of patients were blepharitis, eye irritation, headache, and urinary tract infection.

300

One of the Academy's founding goals was to establish standards for these two key areas of optometric practice.

What are eye examinations and clinical practice?

300

This tear film layer, produced by the Meibomian glands, is often deficient in evaporative Dry Eye Disease.

What is the lipid layer?

300

Before becoming Star Wars: Galaxy's Edge, this area of Disneyland immersed guests in the future.

What is Tomorrowland?

400

Results from the COAT Trial demonstrated improvements in multiple signs and symptoms of dry eye disease within this many days of treatment.

What is 28 days?

400

The AAOPT 2023 Phase 4 CEQUA study demonstrated sustained improvement through this final study time point.

What is Week 12?

400

This test commonly uses a fluorescein dye to evaluate damage to the corneal surface caused by Dry Eye Disease.

What is corneal staining?

400

This attraction was the last one Walt Disney personally supervised before his death.

What is Pirates of the Caribbean?

500

At 3 months in the Phase 3 CEQUA studies, this percentage of patients achieved completely clear central corneas.

What is 65%

500

The William C. Ezell Fellowship, one of optometry's most prestigious research awards, was established in this year.

What is 1949?

500

This inflammatory marker is elevated in some patients with Dry Eye Disease and can be measured using the InflammaDry® test.

What is MMP-9 (Matrix Metalloproteinase-9)?

500

The Disneyland Railroad has stations in all of these lands except one.

What is New Orleans Square?