Fun Facts?
Mechanism of Action
Category is
Resistance Insistance
Completely Unrelated
100
32.) Which of the following is not true about antibiotic resistance?
It is currently a leading cause of death worldwide
It is widespread throughout many bacterial species
There are organisms that we can't treat
CDC and WHO are super concerned
All are true
All are true
100
What mechanism of action describes Nisin?
combine with Lipid II to form pores in membrane or some version of forming pores
100
Nitroimidazoles belong to which category? (CW, CM, PS, NA, M)
Nucleic Acid synthesis inhibition
100
Which of the following 6 reasons describes this reason for increasing antibiotic resistance: Over 80% of antibiotics prescribed by dentists are unnecessary
Over-prescribing antibiotics
patient non-compliance
poor infection control in hospitals
lack of hygiene and poor sanitation
over-use of antibiotics in livestock
lack of new antibiotics
over-prescribing antibiotics
100
What was the last year Butler appeared at the basketball national championship?
2011
200
34.) Selective pressures that result in beneficial mutations being passed onto offspring is an example of what?
Vertical transmission
200
What mechanism of action best describes macrolides?
Bind to 23S rRNA of 50S subunit and inhibit both peptidyl transferase and translocation
200
Pyrazinamides belong to which category? (CW, CM, PS, NA, M)
Cell membrane disruption
200
Which of the following 6 reasons describes this reason for increasing antibiotic resistance: Billions of masks polluting rivers, oceans, fields
Over-prescribing antibiotics
patient non-compliance
poor infection control in hospitals
lack of hygiene and poor sanitation
over-use of antibiotics in livestock
lack of new antibiotics
lack of hygiene and poor sanitation
200
T/F: Schmelz worked at CVS.
False, Walgreens
300
35.) If you want to inhibit bacterial cell's ability to perform transduction, which of the following drugs would you create?
Drug preventing attachment of F pilus
Drug degrades extracellular DNA from environment
Drug inhibits attachment of proteins of viruses
Drug inhibit attachment of proteins of viruses
300
What mechanism of action best describe sulfonamides?
Competitively inhibit dihydropteroate synthetase
300
Cycloserines belong to which category? (CW, CM, PS, NA, M)
Cell wall synthesis inhibition
300
Which of the following 6 reasons describes this reason for increasing antibiotic resistance: Stopping Z-pak course early because "you're better now"
Over-prescribing antibiotics
patient non-compliance
poor infection control in hospitals
lack of hygiene and poor sanitation
over-use of antibiotics in livestock
lack of new antibiotics
patient non-compliance
300
Number of DeAmicis wives that we know of
2
400
16.) Which of the following antibiotics binds to nucleotides?
Clofazimine
Dapsone
Isoniazid
Pyrazinamide
Rifamycin
Clofazimine
400
Which antibiotic does this: bind to 30S subunit and inhibit tRNA from entering A-site?
tetracycline
400
Bacitracin belong to which category? (CW, CM, PS, NA, M)
Cell wall synthesis inhibition
400
Which of the following 6 reasons describes this reason for increasing antibiotic resistance: limited profitability within drug market
Over-prescribing antibiotics
patient non-compliance
poor infection control in hospitals
lack of hygiene and poor sanitation
over-use of antibiotics in livestock
lack of new antibiotics
lack of new antibiotics
400
Fist my ____
bump
500
Describe antibiotic bedaquiline (mechanism of action) and give a drug resistant pathogen that it treats
targets ATP synthase and is used against MDR-TB
500
Mechanism of action describes which antibiotic: target DNA gyrase and topoisomerase IV, preventing DNA replication
Quinolone
500
Aminoglycosides belong to which category? (CW, CM, PS, NA, M)
Protein synthesis inhibition
500
Which of the following 6 reasons describes this reason for increasing antibiotic resistance: An 8% disinfectant rate of stethoscope between patients
Over-prescribing antibiotics
patient non-compliance
poor infection control in hospitals
lack of hygiene and poor sanitation
over-use of antibiotics in livestock
lack of new antibiotics
poor infection control in hospitals
500
Where did Trombley get his PhD?
IU School of Medicine
600
Beta-lactams belong to which category of drug?
CW synthesis inhibitors
600
The following mechanism of action describes which antibiotic: bind to 23S rRNA in the 50S subunit and inhibit ribosomal assemby
Oxazolidinone
600
Polymyxins belong to which category? (CW, CM, PS, NA, M)
Cell membrane disruption
600
Which of the following 6 reasons describes this reason for increasing antibiotic resistance: Undercooked meat and unwashed produce
Over-prescribing antibiotics
patient non-compliance
poor infection control in hospitals
lack of hygiene and poor sanitation
over-use of antibiotics in livestock
lack of new antibiotics
over-use of antibiotics in livestock
600
What is Canela's middle name?
Hugo