RTC Lecture 1
What is one of my many 'ingredients' to a Randomized Clinical Trial?
Control group
What View do the Hellmans adopt instead of utilitarianism?
They adopt a Kantian/deontological view
What does RCT stand for?
Randomized Clinical Trial
What is RTC
A way to do research on human subjects
True or False: Hellman and Hellman reject utilitarian justifications for RTCs
True
Why does Royall criticize randomization?
“The physician must act in the patient’s best interest… not… according to the design of the experiment.”
Beneficence says a healthcare provider should do what?
Promote a Patient's welfare
Who quoted: 'The randomized clinical trial requires doctors to act simultaneously as physicians and as scientists. This puts them in a difficult and sometimes untenable position.'?
Hellman and Hellman
What is the goal of an RCT?
To determine which treatment is more effective
Who is the most notorious physician in history?
Josef Mengele
True or false: The Hellmans think clinical equipoise is rare.
True
According to Royall, when is randomization unethical?
“A physician… should not allow a random device to determine the treatment.”
What is clinical equipoise?
Ethical requirement that true uncertainty must exist before assigning patients to treatment vs. placebo.
Who quoted: 'The greater certainty obtained with a randomized clinical trial is beneficial, but that does not mean that a lesser degree of certainty is without value. Can physicians acquire knowledge through methods other than the randomized clinical trial.'?
Hellman and Hellman
Who quoted: 'The third advantage of randomization that is commonly cited relates to the probabilities used in statistical analysis.'?
Royall