Compensatory Responses to Heart Failure
Pathology of Valvular Heart Disease
Pathological manifestations in heart failure
Pharmacology
PES/History Taking
100

The inability of the heart to pump sufficient blood to meet the body's needs

What is heart failure?

100

The most commonly affected valve in chronic rheumatic heart disease

What is mitral valve?

100

A passive process caused by impaired venous drainage

What is congestion?

100

Drug class that inhibits cell wall synthesis

What are β-lactams?

100

A palpable vibration caused by turbulent blood flow

What is a thrill?

200

Failure of a valve to open completely, causing obstruction to forward blood flow

What is stenosis?

200

Rheumatic fever typically develops approximately this long after streptococcal pharyngitis

What is approximately 3 weeks?

200

Extravasation of blood from vessels

What is haemorrhage?

200

The ability of bacteria to no longer be killed by drugs that were previously effective against them

What is antimicrobial (or antibiotic) resistance?

200

These are painful nodules on the fingers associated with infective endocarditis

What are Osler's Nodes?

300

When the ventricle is already operating near maximum capacity, additional fluid causes this major complication

What is oedema?

300

The most common causative organism of native valve infective endocarditis (Full name)

What is Streptococcus viridans?

300

A state of circulatory failure that impairs tissue perfusion and leads to cellular hypoxia

What is shock?

300

Bacteria that can produce the enzyme penicillinase

What is Staphylococcus aureaus?

300

The patient should be positioned at approximately this angle when assessing JVP

What is 45 degrees?

400

Dyspnoea, orthopnoea and crackles are characteristic of this type of heart failure

What is left-sided heart failure?

400

The organism classically associated with infective endocarditis in intravenous drug users (Full name)

What is Staphylococcus aureus?

400

Accumulation of fluid:
•High protein content
•+/- cells, +/- fibrinogen
•Specific gravity >1.015

Due to increased vascular permeability.
Inflammatory.
Typically seen in bacterial pneumonia.

What is exudate?

400

Colloquially known as a "middle ear infection" and mostly common in children

It frequently follows an upper respiratory tract infection and presents with acute onset severe pain in 1 or both ears

Otitis media

400

A pansystolic murmur radiating to the axilla (i.e. what does this tell us)

What is mitral regurgitation?

500

Cardiac output can no longer be maintained and symptoms occur even at rest

What is decompensated heart failure?

500

The immunological target that antibodies against streptococcal M protein cross-react with

What is type IV collagen/host connective tissue antigens?

500

A patient develops:

  • Massive anterior MI
  • Pulmonary oedema
  • Hypotension

Despite adequate blood volume

What is cardiogenic shock?

500

Prompt treatment of streptococcal pharyngitis with penicillin helps prevent this immune-mediated disease

What is acute rheumatic fever?

500

A patient has:

  • Irregularly irregular pulse
  • Variable intensity S1
  • No obvious repeating pattern

What would be the diagnosis?

What is atrial fibrillation?