Hyabusa
Endpoints
Wildcat
Halaven PI
Dacogen PI
100
The Era of Transformation
What is the meaning of Hyabusa
100
Time from randomization until death from any cause
What is overall survival
100
Aug 26th
What is Frank's birthday
100
12%
What is the % of neutropenia that lasted more than 1 week.
100
15 mg/m2 by continuous intravenous infusion over 3 hours repeated every 8 hours for 3 days. Repeat cycle every 6 weeks. (2.1)
What is treatment regimin 1
200
2011 - 2015
What is the years for the Hyabusa plan
200
time from randomization until tumor recurrence or death from any cause
What is disease free survival
200
Frankie
What is Frank's son's name
200
1.1 mg/m2 over 2 to 5 minutes on days 1 and 8 of a 21 day cycle.
What is the dose of Halaven for pts with Mild Hepatic Impairment and moderate renal impairment
200
20 mg/m2 by continuous intravenous infusion over 1 hour repeated daily for 5 days. Repeat cycle every 4 weeks. (2.2)
What is treatment regimine 2
300
Halaven / Levatinib / farletuzimab
What are the three Oncology products expected to launch during Hyabusa
300
proportion of patients with reduction in tumor size by a predefined amount for a minimum period of time
What is overall response rate
300
Phoenix Arizona
What is David's home state
300
fetal harm
What does halaven cause is pregnant women?
300
1. Neutropenia and thrombocytopenia: Perform complete blood counts and platelet counts. (5.1) 2. Pregnancy: Can cause fetal harm. Advise women of potential risk to the fetus (5.2, 8.1) 3. Women of childbearing potential and men with female partners of childbearing potential should use effective contraception and avoid pregnancy (5.3, 5.4)
What is Dacpgen 3 primary WARNINGS AND PRECAUTIONS
400
Halaven and Perampanel
What are the two "block buster" drugs planned for Hyabusa
400
time from randomization until objective progression
What is time to progression
400
Henry
What is Frank's middle name.
400
ANC < 1000 Platelts < 75000 Grade 3 / 4 Heme toxicities
What is when you should not administer Halaven
400
17% in Dacogen-treated patients and 0% in the SC group
What is The overall response rate (CR+PR) in the ITT population
500
2 Billion dollars
Revenue Target for Oncology by 2015
500
time from randomization to discontinuation of treatment for any reason.
What is time of treatment failure
500
Enzo
What is my dog's name
500
82% and 83%
What is % of the patients in the trial were women and what % were caucasion?
500
What AE was 90% in Dacogen Arm vs 72% in Supportive Care Arm
What is Neutropenia