Pre-Work
Redemption Arc
Redemption Arc
This acyanotic lesion is characterized by a narrowing or obstruction of the aorta (typically the descending aorta)
What is Coarctation of the Aorta (CoA)?
This drug class is used to manage PDA closures
What are non-steroidal anti-inflammatory drugs (NSAIDs)?
This classification system is used instead of NYHA Classification in infants and young children with heart failure
What is the Ross Classification?
All patients with CHD should receive structured patient-centered education that includes these 5 main aspects
What is (1) Their specific CHD diagnosis, including name, anatomy/physiology, and surgical procedures; (2) Expected short- and long-term medical issues; (3) Reproductive health education; (4) Development of independent skills related to health system navigation and access; (5) Need for lifelong uninterrupted care by an ACHD cardiologist
This is the initial dosing recommendation for enalapril in pediatric heart failure
What is 0.1 mg/kg/day in 1 to 2 divided doses?
This cardiac directional shunt occurs in patients with ASD
What is a left-to-right shunt?
This heart failure therapy was approved by the FDA in 2024 as a sprinkle capsule
This type of testing has a Class I (LOE: C) recommendation for pediatric patients affected with any subtype of cardiomyopathy
What is comprehensive or targeted panel genetic testing?
Patients with adult CHD and cyanosis should be screened this often for iron deficiency
What is annually?
This is the initial dosing recommendation for alprostadil in the maintenance of ductus arteriosus patency
What is 0.05 to 0.1 mcg/kg/minute?
In hypercyanotic episodes, this intervention is recommended first to increase SVR
What is placing the patient in a knee-to-chest position?
This medication is used to maintain patency of the ductus arteriosus when necessary (provide the names of the synthetic and endogenous forms)
What is alprostadil (synthetic) and prostaglandin E1 (endogenous)?
The results from this RCT demonstrated the safety/efficacy of sacubitril/valsartan compared to enalapril in pediatric patients with heart failure
What is PANORAMA-HF?
This is the blood pressure goal for adults with native or repaired CoA
What is < 130/80 mmHg?
In this congenital heart defect, the aorta is positioned to the left and front of the pulmonary artery, with ventricular inversion (be specific)
What is levo-transposition of the great arteries (also known as L-type TGA or congenitally corrected TGA)?
In hypercyanotic episodes, this treatment may be used to decrease dynamic right ventricle outflow tract obstruction, and may also help with sedation and blunting tachypnea
What is morphine (IV)?
This SGLT2 inhibitor's brand and generic names are the most frequently referenced in the pediatric heart failure literature
What is dapagliflozin (Farxiga)?
This pharmacological intervention has a Class 1 recommendation for adults with Fontan circulation and the absence of high-risk features
What is aspirin or anticoagulation?
These are the three procedures (named sequentially) that are performed in patients with hypoplastic left heart syndrome (HLHS)
What are the (1) Norwood, (2) Glenn, and (3) Fontan?
Double Whammy: The brand name of this endothelin-1 receptor antagonist is utilized for pulmonary arterial hypertension associated with CHDs, and is only available through a REMS program because of this major safety concern
What is TRACLEER (brand name)? and What is hepatotoxicity?
This enzyme replacement therapy's Brand name is recommended in the ISHLT 2024 guidelines in patients with Hunter Syndrome
What is Elaprase (generic name: idursulfase)?
An adult patient with HFrEF, PAH, and Eisenmenger Syndrome is currently taking bosentan and tadalafil, but is still experiencing symptoms. Would prostacyclin analogs be appropriate at this time?
No.
"In adults with Eisenmenger syndrome and LV ejec-tion fraction >40% who are deemed to be at highrisk for adverse outcomes†or who have rapidlyprogressive disease, inhaled or subcutaneousprostacyclin therapy may be considered as initialtherapy or as an addition to other PAH therapyto improve symptoms, exercise capacity, andhemodynamics." (COR 2b/LOE C-LD)