Fine, yes, it is a Jojo reference.
This must be the effect of a Stand...
Alternate Names That Aren't From The Dub
Real Facts About Hirohiko Araki
No, that's not actually true.
400

By Hideki Kamiya's own admission, the locker labeled "Jonathan" in this PS1 classic is a deliberate reference.

Resident Evil 2

400
Every series in Shonen Jump that came after Jojo's owes its ability for protagonists to do this while continuing the story.

Die.

400

Wanna pick a fight with a Steel Ball Run fan? Use this official name for its major Native American protagonist, whose correct spelling is a spoiler.

Sandman

400

Araki has met this actor, whose work on films like A Fistful of Dollars and Gran Torino were major influences on Jotaro.

Clint Eastwood

400

No, Josuke was never meant to go back in time and become his own savior. Araki's given this official statement on the savior's identity.

IT DOESN'T MATTER. 

800
This Persona spin-off has the Persona 4 cast introduced with various iconic Jojo poses. If you start P4 discourse off of this question, I will kill you in real life.

Persona Q: Shadow of the Labyrinth.

800

The titular mechanic in this Playstation RPG series is a pretty obvious sendup to stands.

Persona

800

The Capcom fighter's English version was... less than creative when trying to skirt around copyright, leading to names such as J. Gale, D'Bo, and this name for Justice's elderly user. 

N-yah Gail

800

Araki's art has been displayed in numerous non-manga locations and mediums, including this famous museum.

The Louvre

800
No, Avdol's first death in Part 3 was never meant to be permanent. As a matter of fact, this supposed reason he was brought back doesn't hold up to scrutiny.

Popularity polls, where Avdol placed last.

1200

Koji Igarashi is clearly a big fan of the series, since nearly every one of his Castlevanias has a reference, but this fight in Dawn of Sorrow is a direct and obvious homage to Dio.

Zephyr

1200

Though its true origin lies elsewhere (arguably Juno, from the Epic of Gilgamesh), Yukako Yamagishi is often credited for popularizing this character trope.

Yandere

1200

Araki, for once, actually forgot that he had already used this name for the stand now known as Planet Waves.

Earth Wind and Fire

1200

Araki has done many interviews with this singer/actress, who is an open fan of Jotaro and openly desires to be his unloved wife.

Shoko Nakagawa

1200

No, Jotaro's Time Stop doesn't put any sort of strain on his heart. The origin for this is likely conflating him with a character from this series

Code Geass

1600

Polnareff and Stroheim's hairstyles served as inspiration for this Street Fighter classic.

Guile

1600

CLAMP, authors of Cardcaptor Sakura and character designers for Code Geass, tend to reinvent their interpretation of this Jojo ship in their works.

Jotaro/Kakyoin

1600

For unknown reasons, this initial name for Made in Heaven didn't survive the transition to the volume release.

Stairway to Heaven

1600
In the year 2000, Araki named this series as his favorite manga.

Golgo 13

1600

No, Cream wasn't the first stand to be named after music. It is chronologically, but he wasn't given a name until this artbook, released well after Part 4.

Jojo 6251

2000
In the first Windows-era Touhou game, Embodiment of Scarlet Devil, Remilia tries to pull Dio's "how many breads" question, but Marisa shuts it down by saying this.

"Thirteen. I prefer Japanese food."

2000

This iconic vampire killer's seiyuu got his role because of his work as Jotaro in the Part 3 Drama CD.

Richter Belmont

2000

Ever wonder what's up with the name of the Capcom fighter? It's actually an official name for Part 3, used in this scenario.

The initial serialization in Weekly Shonen Jump

2000

Araki has actually explained how he maintains his youthful appearance. He simply washes his face with this.

Tap water fresh from Mt. Fuji.
2000

No, despite his hole-filled outfit, Fugo is not designed around cheese. His original manga coloration, name, and shoes all point to this food theme, instead.

Strawberries.