This cell line was originally isolated and grown by Dutch biologist Alex Van der Eb in the early 1970s -partially named for the successful experimental number.
HEK 293
This genus of yeast gets its name from Latinized Greek and means "sugar-mold" or "sugar-fungus"
Saccharomyces
DMSO - a reagent commonly used in cell storage media
Dimethylsulfoxide
This strain of virus caused the 2009 swine flu pandemic - also the subject of a seminal Kormuth et al., 2018 study
H1N1
Carnegie Mellon University is named for which two people (first and last names)
Andrew Carnegie and Andrew Mellon
Cervical cancer cells taken from this woman in 1951 generated one of the most widely utilized immortal cell lines used in biological research. (name the woman)
Henrietta Lacks
Also known as "fission yeast" this yeast species diverged from "baker's yeast" approximately 600 to 300 million years ago, and are significant tools in the study of DNA damage and repair mechanisms (genus and species)
Schizosaccharomyces pombe
snoRNA -a class of small RNA molecules that primarily guide chemical modifications of other RNAs
small nucleolar RNA
Plague! aka the Black Death that wiped out 75-200 million people was not caused by a virus, but instead by this bacteria
Yersinia pestis
Where is the 4th river in Pittsburgh according to Jon Jarvik
the Mellon Insitute Basement
A cell-type in the brain, it's name comes from the *Ancient* Greek for 'star'
Astrocyte
Yeast most commonlyreproduce asexually by budding - creating a daughter cell, also known as a this.
a bleb
ATCC - a repository of commercially available cell lines and reagents
American Type Culture Collection
This University of Pittsburgh professor developed one of the first successful vaccines against Poliovirus; he's widely credited with eradicating Polio
Jonas Salk
Which Biology PhD student was an extra in the movie, The Dark Knight Rises, when it was filmed in Pittsburgh?
Rachel Vistein
This is a type of cell that synthesizes the extracellular matrix and collagen. The suffix in it's name denotes a stem cell or a cell in an activated state of metabolism.
Fibroblasts
This species is an opportunistic pathogenic yeast that is a common member of the human gut flora.
Candida albicans
CRISPR - a gene editing tool
Clustered regularly interspaced short palindromic repeats
Lyssa, from the Greek "rage, fury" is the genus of this virus that is primarily transmitted from animals to humans through saliva. Disease associated with this virus is nearly always fatal after onset of symptoms.
Rabies
What is the name of the Woolford-Puthenveedu lab member social group?
Woolveedu
The name 'cell' was first coined by this man in 1665 who commented that "it looked strangely similar to cellula or small rooms which monks inhabited"
Robert Hooke
In 1996, S. cerevisiae became the first eukaryote to have its genome completely sequenced as part of the Genome Project. The full genome is how many base pairs (+/- 1 million)
12 Million
What are the three elements that define the CAG expression promoter (one element for each letter) ?
C- cytomegalovirus early enhancer
A- chicken beta actin gene (first exon and intron)
G- rabbit beta globin gene (splice acceptor)
The HxNx nomenclature of Influenza A viruses detail the subtype of their major antigenic determinants. What does the "H" stand for?
Hemagglutinin
Which beloved potato chip shaped building was removed from the CMU campus?
Scaif Hall