General pharmacy
A drug exhibits concentration-dependent killing, a prolonged post-antibiotic effect, and nephrotoxicity that correlates better with trough concentration than peak concentration. Traditionally, multiple daily doses were used, but later, once-daily dosing became preferred.
Question: Which antimicrobial class fits this paradox, and why does extended-interval dosing reduce toxicity?
Aminoglycosides.
Once-daily dosing allows lower troughs and a drug-free period, reducing renal cortical accumulation while preserving efficacy due to concentration-dependent killing and post-antibiotic effect.
Which Act governs pharmacy practice in Kenya?
Pharmacy and Poisons Act (Cap 244)
Which Kenyan resistance leader was exiled to Kisii and later to the Seychelles by the British after leading resistance against colonial rule?
Koitalel Arap Samoei
In Formula 1, what does DRS stand for?
Drag Reduction System
Which country has the most pyramids in the world?
Sudan
Which parameter is used to assess powder flow based on the height and radius of a pile?
Angle of repose
Which receptor subtype is primarily responsible for morphine-induced euphoria?
μ1 (mu-1) opioid receptor
How old was Michael Jackson when he died, and what killed him?
50 years and Propofol
A weak base with pKa = 8.0 enters gastric fluid at pH 2 and plasma at pH 7.4.
Question: In which compartment is it trapped, and what pharmacokinetic phenomenon explains it?
Trapped in gastric fluid.
Phenomenon: ion trapping.
What is the legal requirement for dispensing controlled drugs in Kenya?
It must be recorded in a controlled drugs register
Which Kenyan politician was assassinated in 1969 and had founded KPU?
Tom Mboya
What is the recent world record marathon time, and who set it?
1:59:30 & Sabastian Sawe
What is the only continent through which the Equator, Tropic of Cancer, and Tropic of Capricorn all pass?
Africa
What is the main function of magnesium stearate in tablet formulation?
Lubricant
Which anticoagulant acts by inhibiting factor Xa indirectly via antithrombin III?
Fondaparinux
Which actor has portrayed both a Marvel superhero and a DC superhero in major films: Human Torch and Captain America?
Chris Evans
A patient with atypical plasma cholinesterase receives a neuromuscular blocker and develops prolonged apnea after surgery.
Question: Which drug was most likely given?
Succinylcholine
What schedule are most prescription-only medicines classified under?
Part I of the Poison List (Prescription Only Medicines – POMs)
Which event triggered the declaration of the State of Emergency in Kenya in 1952?
Intensification of Mau Mau activities and assassination of Senior Chief Waruhiu
Which country invented table tennis?
England
Which scientist proposed the three laws of planetary motion?
Johannes Kepler
Which defect occurs when tablets split horizontally after compression?
Capping
Which drug reverses warfarin-induced bleeding immediately?
Prothrombin complex concentrate (PCC)
Which TV series holds the record for the most Emmy wins for a scripted show?
Game of Thrones
Which antimicrobial inhibits peptide elongation by preventing translocation from the A site to the P site on the 50S ribosomal subunit?
Erythromycin
Which professional body represents pharmacists in Kenya?
Pharmaceutical Society of Kenya
Which war was sparked by the assassination of Archduke Franz Ferdinand?
World war I
Which player has played for both Chelsea and Man City and is a Ballon d'Or winner?
George Weah, the president of Liberia
What is the smallest unit of life capable of independent existence?
Cell
What is the standard pore size for sterile membrane filtration?
0.22 micrometers
What is the major toxic metabolite of paracetamol?
N-acetyl-p-benzoquinone imine (NAPQI)
Which TV station aired the Kenyan drama series “Selina”?
Maisha Magic East
A poison causes severe lactic acidosis, bright red venous blood, and the inability of tissues to utilize oxygen despite normal oxygen delivery.
Question: What toxin is responsible?
Cyanide
Which category of medicines requires duplicate prescription retention in Kenya?
Narcotics
Which present-day African country was formerly called Upper Volta?
Burkina Faso
Who are the defending NBA champions?
Oklahoma City Thunders OKC
Which African country has Portuguese as its official language?
Mozambique
Which test predicts long-term stability in a short time?
Accelerated stability testing
Which drug is a competitive antagonist at NMDA receptors used in Alzheimer’s disease?
Memantine
Which Kenyan musician founded the record label “Konvict Kulture Kenya”?
Nviiri the Storyteller
Which pharmacokinetic parameter mathematically equals the following?
0.693 × Vd / Clearance
Elimination half-life
Which register contains licensed pharmacists in Kenya?
Pharmacists Register
Which African country has changed its name the most in modern history?
Mali(French Sudan → Sudanese Republic → Mali Federation → Republic of Mali)
Which cricketer has the highest individual score in one-day internationals?
Rohit Sharma
Which treaty officially dissolved the Austro-Hungarian Empire after World War I?
Treaty of Saint-Germain-en-Laye |
What type of flow shows decreasing viscosity with increasing shear?
Pseudoplastic flow
Which drug causes the “steal phenomenon” in the coronary circulation?
Dipyridamole
Which Kenyan DJ is popularly known as “The Entertainer”?
DJ Joe Mfalme