Steps
Steps (contd.)
Enzymes
Molecules
Tidbits of Krebs Cycle
100

When oxygen is available, the pyruvate produced during glycolysis moves into the matrix of the mitochondria, where it undergoes an oxidation reaction, where carbon dioxide is released and NADH and aceytl-CoA are produced

What is pyruvate oxidation?

100

GDP forms GTP after a phosphate molecule replaces the CoA in succinyl-CoA. This creates this molecule

What is succinate?

100

The enzyme that helps change aceytl-CoA and oxaloacetate into citrate

What is citrate synthase?

100

In step 5, the GTP formed transfers its phosphate to ADP to form this molecule

What is ATP?

100

DAILY DOUBLE

The Krebs Cycle was first identified by this German physician and biochemist in 1937

Who is Sir Hans Adolf Krebs?

200

It is the product acetyl-CoA and oxaloacetate

What is citrate?

200

It oxidizes succinate to form FADH2 and fumarate

What is FAD?

200

An isomerase that changes citrate into isocitrate

What is aconitase?

200

This molecule is produced in the third and fourth steps of the Krebs cycle

What is carbon dioxide (CO2)?

200

The Krebs Cycle takes place in this part of the cell

What is the mitochondria?

300

Citrate is reconfigurated to form this molecule

What is isocitrate?

300

Water is added to fumarate to form this molecule

What is malate?

300

The enzyme that changes succinate into fumarate

What is succinate dehydrogenase?

300

This molecule is produced when NAD+ oxidizes isocitrate in the third step,

What is NADH?

300

Another name for the Krebs Cycle. This substance can be found in foods such as oranges and lemons

What is the citric acid cycle?

400

It is formed from NAD+ oxidizing isocitrate to form oxalosuccinate intermediate, which immediately loses CO2 

What is

400

Another NAD+ oxidizes malate to form NADH and this molecule. It is then ready to combine with another acetyl-CoA entering the cycle

What is oxaloacetate?

400

DAILY DOUBLE:

The enzyme that changes fumarate into malate

What is fumarase?

400

This molecule is one of the products of pyruvate oxidation and the first molecule that is present in the Krebs cycle

What is aceytl-CoA?

400

The Krebs Cycle is the third step in this biological process

What is cellular respiration?

500

NAD+ loses another CO2 and combines with coenzyme A to form this molecule

What is succinyl-CoA?

500

The net production for each for each molecule of acetyl-CoA

What is 3 NADH, 1 FADH2, 1 ATP?

500

The enzyme that changes malate into oxaloacetate?

What is malate dehydrogenase?

500

The most important biological molecule is present in the Krebs cycle during steps 1 and 7

What is water (H2O)?

500

Although the use of oxygen is not directly involved in the Krebs cycle, it is considered this kind of process

What is aerobic process?