Method of Action
This drug class disrupts cell wall synthesis.
What are beta lactams?
These drug classes are time dependent (name 3).
The bacterial spectrum for beta-lactams.
What is gram positive, some gram negative, and some anaerobic (depending on beta-lactam class)?
Contact with this drug can cause aplastic anemia in humans.
What is chloramphenicol?
Penicillin options in large animal medicine?
What are procaine penicillin G/PPG (IM) and potassium penicillin G/KPen (IV)?
These drug classes act on the 30s ribosome to disrupt protein synthesis.
What are aminoglycosides and tetracyclines?
These drug classes are considered bacteriostatic (name 3).
What are macrolides, tetracyclines, chloramphenicol, non-potentiated sulfonamides?
The bacterial spectrum for aminoglycosides.
These drug classes can result in IMHA/IMTP.
What are potentiated sulfonamides and beta-lactams?
Cephalosporin options commonly available in large animal.
[cefotaxime, cefpodaxime, cefopime, cequinone]
These drug classes act on the 50s ribosome to disrupt protein synthesis.
What are macrolides and chloramphenicol?
These drug classes are considered bacteriocidal (name 3).
What are beta-lactams, aminoglycosides, potentiated sulfonamides, rifampin, fluoroquinolones, metronidazole, vancomycin?
(high doses macrolides and tetracyclines)
The bacterial spectrum for tetracyclines.
What is rickettsial, anaplasma/ehrilichia, variable Gram +/-, variable anaerobes?
These drug classes can cause nephrotoxicity.
What are aminoglycosides and tetracyclines (oxytet)?
Tetracyclines available in large animal medicine.
What are fluoroquinolones?
These drug classes are considered concentration dependent (name 3).
What are aminoglycosides, fluoroquinolones and metronidazole.
The bacterial spectrum for fluoroquinolones.
What are gram negative aerobes, staphylococcus and corynebacterium?
These drugs can have neurologic side effects.
What are penicillin (PPG) and metronidazole (IV)?
What is enrofloxacin? (ciprofloxacin and ofloxacin for ophtho)
This drug class prevents DNA synthesis by inhibiting folic acid synthesis.
These drug classes are water soluble (rest are lipid soluble).
What are beta-lactams, aminoglycosides, and vancomycin?
The bacterial spectrum for rifampin.
What is narrow: staph, strep, rhodococcus equi, mycobacterium, coryne? (always used in combo, rapid resistance)
This drug class can cause life-threatening colitis in adult horses.
What are macrolides?
Macrolides available in large animal medicine.