Toy Box Tidbits
The Discrepancy Zone
The Phenotype Files
Panagglutination Problems
QC or Not QC
100

This fictional pizza company appears throughout the Toy Story franchise.

Pizza Planet

100

This term describes red blood cells that appear stacked like coins due to excess plasma proteins.

Rouleaux

100

This chemical treatment renders red cells DAT‑negative while preserving most antigens (except for Kell BGS antigens), allowing accurate phenotyping.

EGA

100

This drug causes weak panagglutination with all reagent cells tested by IAT and requires DTT‑treated cells to resolve the interference.

DARA (anti-CD38)

100

This platelet product is created using UV technology.

Intercept (pathogen reduced) platelets

200

This floppy‑eared canine is the breed of Andy’s dog, Buster, in Toy Story.

 

Dachshund

200

This plant‑derived lectin, used to distinguish A1 from A2 red cells, helps resolve ABO discrepancies caused when an A2 or A2B individual produces an anti‑A1.

Dolichos biflorus

200

This technique allows phenotyping of sickle cell patients by separating transfused donor red cells from the patient’s own cells.

Hypotonic wash

200

This technique is used to rule out underlying clinically significant antibodies when a warm autoantibody masks all IAT reactivity and the patient’s phenotype cannot be obtained.

Differential adsorption

200

According to AABB standards, this is the minimum number of platelets required in a single unit of apheresis platelets.

3.0 × 10¹¹ platelets

300

This Toy Story movie is where Barbie makes her first appearance

Toy Story 2

300

This rare phenotype appears as group O in routine testing, yet is incompatible with nearly the entire donor population.

Bombay Phenotype

300

This LifeSouth‑used antisera is performed by IAT and requires a 2‑to‑1 ratio of antisera to red cell suspension.

Anti-Wra

300

This reagent, containing both DTT and ficin, is used to prepare red cells for adsorption by removing bound antibodies and enhancing antigen exposure.

ZZAP (W.A.R.M)

300

This value represents the acceptable pH range required for quality control of platelet products.

≥ 6.2

400

This character delivers the iconic line, ‘You’re a sad, strange little man.'

Buzz Lightyear

400

This reagent - commonly used to adsorb interfering cold autoantibodies - can itself create an ABO discrepancy by inadvertently removing clinically significant IgM antibodies such as anti‑B.

RESt

400

This chemical renders red blood cells DAT‑negative and also destroys Bga antigens.

Chloroquine diphosphate (GammaQuin)

400

This term describes nonspecific panagglutination of red cells with human serum after exposure of RBC ‘cryptantigens.’

Polyagglutination

400

According to AABB standards, this is the maximum number of residual leukocytes permitted in platelet or red cell components.

fewer than 5 × 10⁶ WBCs

500

This is the name of the daycare center featured in Toy Story 3.

Sunnyside Daycare

500

This rare ABO discrepancy occurs when certain gram‑negative bacteria modify the A antigen.

Acquired B

500

Individuals from this race may express the phenotype K–, k+, Kpᵃ–, Kpᵇ+, Jsᵃ+, Jsᵇ–

African American/Black

500

This antibody should be suspected when a patient from India shows panagglutination at the IAT phase, with reactivity destroyed by both ficin and DTT.”

Anti-Inb

500

This is the minimum required amount of fibrinogen, in milligrams, that must be present in a unit of cryoprecipitated AHF according to AABB standards.

150 mg per unit