Microbiology
Hematology
Chemistry
Urinalysis
Hardest Questions I've Ever Seen
100

The India ink stain is used as a presumptive test for the presence of which organism?

Cryptococcus neoformans in CSF

100

Which is the cause for most strokes and heart attacks in the United States?

a. Hemorrhage

b. Thrombocytopenia

c. Cancer

d. Consequences of thrombotic events

d. Consequences of thrombotic events

About 80% of heart attacks and 85% of strokes in the United States are caused by thrombi that block coronary or carotid arteries.

100

An emphysema patient suffering from fluid accumulation in the alveolar spaces is likely to be in what metabolic state?

a. respiratory acidosis

b. respiratory alkalosis

c. metabolic acidosis

d. metabolic alkalosis

a (Diseases causing respiratory acidosis.)

100

Which of the following urine results is most apt to be changed by prolonged exposure to light?

a. pH

b. protein

c. ketones

d. bilirubin

d. bilirubin

100

Increased concentrations of ascorbic acid inhibit chromogen production in which of the following glucose methods?

a ferricyanide

b ortho-toluidine

c glucose oxidase (peroxidase)

d hexokinase

c glucose oxidase (peroxidase)

200

What is the first step to be performed in the identification of an unknown yeast isolate?

Germ tube test

200

What is the name of the thrombotic disorder characterised by edema and swelling in limbs?

Deep Vein Thrombosis

200

Bromcresol purple at a pH of 5.2 is used in a colorimetric method to measure: 

a albumin

b globulin

c Bence Jones protein

d immunoprotein

a albumin

200

The creatinine clearance is reported in:

a. mg/dL

b. mg/24 hours

c. mL/min

d. mL/24 hours

c. mL/min

200

The most widely used methods for bilirubin measurement are those based on the:

a Jaffe reaction

b Schales and Schales method

c 8-hydroxyquinoline reaction

d Jendrassik-Grof method

d Jendrassik-Grof method

300

What do you do with a stool sample contaminated with urine?

Do not accept, urine could kill motile organisms

300

What other thrombotic disorder can deep vein thrombosis manifest into?

Pulmonary embolism

300

The biuret reaction for the analysis of serum protein depends on the number of:

a free amino groups

b free carboxyl groups

c peptide bonds

d tyrosine residues

c. peptide bonds

300

Failure to observe RBC casts in a urine specimen can be caused by:

a. staining the specimen

b. centrifuging an unmixed specimen

c. mixing the sediment after decantation

d. examining the sediment first under low power

b. centrifuging an unmixed specimen

300

The International Federation for Clinical Chemistry (IFCC) recommends the use of methods such as the Bessey-Lowry-Brock method for determining alkaline phosphatase activity. The substrate used in this type of method is:

a monophosphate

b phenylphosphate

c disodium phenylphosphate

d para-nitrophenylphosphate

d para-nitrophenylphosphate

400

Primary amoebic encephalitis may be caused by:

Naegleria fowleri

400

A patient's platelet count drops 4 days after being placed on heparin. Select the correct interpretation.

a. The patient has heparin-induced thrombocytopenia.

b. The patient has benign, limited thrombocytopenia related to heparin.

c. A bleeding time should be performed to evaluate qualitative platelet disorders.

d. An immunoassay for heparin-dependent anti-platelet factor 4 (PF4) should be performed to distinguish heparin-induced thrombocytopenia from benign, limited thrombocytopenia related to heparin.

d. An immunoassay for heparin-dependent anti-platelet factor 4 (PF4) should be performed to distinguish heparin-induced thrombocytopenia from benign, limited thrombocytopenia related to heparin.

400

In a pleural effusion caused by Streptococcus pneumoniae, the protein value of the pleural fluid as compared to the serum value would probably be:

a decreased by 2

b decreased by 1/2

c increased by 1/2

d equal

b decreased by 1/2

Abnormal accumulation of serous fluids due to an imbalance of fluid production and reabsorption.Fluid/serum protein ratio .0.5.

400

Which of the following reagents is used to react with ketones in the urine?

a. sodium nitroprusside

b. acetoacetic acid

c. acetone

d. beta-hyroxybutyric acid

a. sodium nitroprusside

400

Which of the following methods for quantitation of high-density lipoprotein is most suited for clinical laboratory use?

a Gomori procedure

b homogeneous

c column chromatography

d agarose gel electrophoresis

b homogeneous

500

A 44 year old man was admitted to the hospital following a 2 week history of low grade fever, malaise and anorexia. Examination of a Giemsa stain revealed many intraerythrocytic parasites. Further history revealed frequent camping trips near Martha's Vineyard and Nantucket Island, but no travel outside the continental US. This parasite easily be confused with:

Plasmodium falciparum

500

What two complications are most commonly associated with arterial thrombosis?

strokes and myocardial infarctions

500

Which of the following methods is susceptible to the solvent displacing effect that results in falsely decreased electrolyte values?

a indirect ion-selective electrodes

b direct ion-selective electrodes

c spectrophotometric

d fluorescence

a indirect ion-selective electrodes

500

A 2-year-old child had a positive urine ketone. This would most likely be caused by:

a. vomiting

b. anemia

c. hypoglycemia

d. biliary tract obstruction

a. vomiting

500

Which of the following calcium procedures utilizes lanthanum chloride to eliminate interfering substances?

a o-cresolphthalein complexone

b precipitation with chloranilic acid

c chelation with EDTA

d atomic absorption spectrophotometry

d atomic absorption spectrophotometry