Tocolytics
Safest med to stop preterm labor at 32 weeks?
Nifedipine
First med for a boggy uterus postpartum?
Oxytocin (Pitocin)
IV med to lower BP in severe preeclampsia?
Labetalol (Trandate)
Antidote for magnesium toxicity?
Calcium gluconate
Which steroid promotes lung maturity?
Betamethasone (Celestone)
Tocolytic that causes maternal tachycardia?
Terbutaline
Which PPH med is contraindicated in asthma?
Hemabate (Carboprost)
Common hydralazine side effect?
Reflex tachycardia
First action if contractions occur every 1 min on oxytocin?
Stop infusion immediately
Earliest gestation for betamethasone?
24 weeks
Why avoid indomethacin after 32 weeks?
Premature ductus arteriosus closure
Which uterotonic should be avoided in HTN?
Methergine
Which class of antihypertensive drugs is contraindicated during pregnancy due to fetal toxicity?
ACE inhibitors (e.g., enalapril, lisinopril) and ARBs (e.g., losartan).
3 signs of magnesium toxicity?
RR <12, absent DTRs, urine output <30 mL/hr
Magnesium sulfate provides what fetal benefit?
Neuroprotection
At how many weeks of gestation are tocolytics typically considered most effective?
Between 24 and 34 weeks of gestation.
Two meds for cervical ripening?
Misoprostol (Cytotec), Dinoprostone (Cervidil)
Which direct vasodilator is sometimes used when other antihypertensive medications fail in hypertensive emergencies during pregnancy?
Hydralazine.
Cytotec is contraindicated for induction of labor in women with a history of _____ and/or _____?
Previous uterine surgery including CS and asthma
Betamethasone dosing schedule?
2 doses, 24 hours apart
Two tocolytics + 1 side effect each?
Nifedipine → hypotension; Terbutaline → tachycardia
Three meds for PPH + 1 contraindication each?
Oxytocin → none; Hemabate → asthma; Methergine → HTN
Two IV meds for hypertensive crisis + why one is preferred?
Labetalol & Hydralazine; labetalol causes less reflex tachycardia
What is the primary obstetric indication for methotrexate administration?
Medical management of unruptured ectopic pregnancy by inhibiting rapid cell division of the trophoblast.
Which medication is administered to newborns of hepatitis B surface antigen (HBsAg)-positive mothers within 12 hours of birth?
Hepatitis B immune globulin (HBIG), along with the first dose of the hepatitis B vaccine.