EFFICACY
Name the number of years of efficacy data that is shown in the new IVA.
What is 6 years?
Name the top 4 most common adverse reactions.
Upper respiratory tract infections, conjunctivitis, injection site reaction, and eosinophilia
This California Park, home of iconic granite cliffs, was the first state park in the U.S.
What is Yosemite National Park.
The term "red face" refers to what AND which competitor has "it" listed as an adverse event in their PI.
What are facial erythema and Dupixent?
True or False: Dupixent is indicated for Chronic Hand Eczema?
False, though indicated for Atopic dermatitis which can include the hands, it is not specifically indicated for "chronic hand eczema."
The ECZTEND study demonstrated a median EASI improvement of 88% at 1 year.
Name the median EASI improvement with Adbry at 4 years AND the length of the treatment gap. (a range is acceptable)
What are 2 months on average and 26 weeks maximum?
In the real-world results with Adbry, what was the pooled proportion reported rate for conjunctivitis?
3.2%
This historic market is famous for its fish throwing and fresh produce.
What is Pikes Place Market.
This biologic utilized a double loading dose in their clinical studies.
What is Ebglyss?
Of the many signs and symptoms of CHE, which two are the most debilitating?
Itch and pain
Name the newest addition to body part images in the IVA and how long the patient was studied between the before and after images.
What are Head & Neck and 10 weeks?
Discontinuation rate reported in long term safety (up to 4.5 years)
5.3%
The only state in the United States that has tropical rainforest and grows coffee, vanilla bean, and cocoa.
What is Hawaii
This biologic competitor requires reconstitution and has Q8W dosing in their label.
What is Nemluvio?
How long must hand eczema last to be considered CHE?
for 3 months or more or relapse more than twice a year
In the ECZTRA 1&2 mono therapy pooled data, there were 3 time periods measured from the 48 hour itch data baseline. Name the 3 time periods.
What are 1 week and week 16?
What is our "No" warnings?
Arthralgia, psoriasis, psoriatic arthritis
This City is home to the "Painted Ladies" which were made famous by the TV show Full House.
What is San Francisco.
This biologic was a second to market IL-13 inhibitor
What is Ebglyss?
What percentage of CHE cases are allergic contact dermatitis?
~22%
In the OLE trial, what was the 4 year median EASI improvement percentage with Adbry and what did it demonstrate?
95% and recapture and durability
What are the rates of conjunctivitis in 16 week monotherapy trials vs. EASI: OLE
7.5% vs 5%
The first live telecast of a nuclear explosion originated in this state in 1952.
What is Nevada.
These 3 AD approved biologic injectable products have monthly dosing as part of their label.
What are Adbry, Nemluvio, Ebglyss
What percentage of CHE patients present with 2 or more subtypes?
More than 50%