Epidemiology/Presentation
This serovar of Leptospira interrogans has dogs as its reservoir host.
What is canicola?
This phase of Leptospirosis leads to extension of infection into organs such as the kidneys, liver, and CNS.
What is the Leptospiremic phase?
This renal condition is a hallmark of Leptospirosis due to tubular necrosis and loss of nephrons.
What is acute kidney injury (AKI)?
This molecular test is used to confirm the presence of Leptospira spp.
What is PCR?
Name one toxic cause of acute kidney injury that could mimic Leptospirosis.
What are grapes/raisins, ethylene glycol, or NSAIDs?
Roaming dogs and dogs exposed to this environmental factor are at higher risk for Leptospirosis.
What is standing water?
Leptospira spp. initially injures these cells before invading parenchymal cells.
What are endothelial cells?
PU/PD in Leptospirosis is caused by this specific renal dysfunction
What is the inability to concentrate urine?
This diagnostic technique involves testing both acute and convalescent serum samples.
What is paired MAT serology?
Leptospirosis should also be differentiated from this category of renal injury caused by reduced blood flow.
What is ischemic injury?
Signalment overrepresented among Lepto cases
What are male dogs?
Leptospiral invasion of the kidneys results in this acute condition that may progress to interstitial nephritis in chronic disease.
What is acute nephritis?
Thrombocytopenia in Leptospirosis is caused by damage to these cells
What are endothelial cells?
These supportive diagnostic tools include imaging and biochemical analysis of kidney function.
What are ABD ultrasound, chem panel, coag profile, and urinalysis?
Lepto enters the body through these two types of contact.
What are skin wounds and MM contact?
This disseminated vascular condition, associated with vasculitis and thrombosis, is a severe complication of Leptospirosis.
What is disseminated intravascular coagulation (DIC)?
The enlargement and pain of the kidneys in Leptospirosis is caused by this inflammatory response.
What is interstitial edema and swelling?
An enlarged kidney in a dog with suspected Leptospirosis can be detected using this imaging method.
What is ABD U/S?