When at a conference or in public, you are the _____ of Loyal.
You are the FACE of Loyal.
Aging is the _________ _____ _____ of changes associated with an __________ _____ of ________ and _______.
Aging is the accumulation over time of changes associated with an increased risk of disease and death.
Name the Core Value: We have the bravery to shoot for the impact that we want to have
Lean into Moonshots
LOY002 is a _________ given ______.
flavor tab given orally
What type of veterinary practice is ideal for our clinical trials?
General Practice
True/False: Open toed shoes are fine to wear to a site visit or conference.
False. Safety first! Cover those toes.
Healthspan is the amount of time lived ........
without significant age-related health problems.
Who is Loyal?
Here at Loyal, we are a team of _______, _______, ________, and _________ working to develop the first-ever drugs intended to extend lifespan and healthspan in dogs.
Who is Loyal?
Here at Loyal, we are a team of veterinarians, scientists, dog lovers, and longevity experts working to develop the first-ever drugs intended to extend lifespan and healthspan in dogs.
We would like to enroll around ____ sites, and _____ dogs.
50 sites and 1000 dogs
Name 3 reasons it's beneficial for a veterinarian/site to be in our clinical trial?
Be a scientist
Gain new skills
Be part of something bigger
Offer cutting edge medicine (and preventative care) to your patients - at no cost to them
Study compensation
Examples of suggested items to bring when visiting a site to show you appreciate them and their time.
Lunch, snacks, cookies. Gift card if visiting remotely.
Dogs and humans experience aging in similar ways and share many of the ____________ _________ and _________ __________ associated with aging.
physiologic changes and clinical diseases
Name the Core Value: Our patients are not numbers. Our work is intentional, thoughtful, and respectful
Empathy and respect for all life
TRUE/FALSE: There is a maximum limit of dogs a single site can enroll
FALSE: There is absolutely no limit on how many dogs a site can enroll, the sky's the limit, but we recommend no less than 15 patients per site
Objection: THIS IS GOING TO BE EXTRA WORK
A study visit will take approximately ___ minutes. And is nearly equivalent to a typical _____ _____ ____.
A study visit will take approximately 60 minutes. And is nearly equivalent to a typical senior wellness visit.
Mastery of moderation when representing Loyal. If consuming alcohol, have ___ drinks or less.
2 Drinks or Less, Please.
Epigenetics is the study of how your _________ and _________ can cause changes that affect the way your ______ _______.
Epigenetics is the study of how your behaviors and environment can cause changes that affect the way your genes work.
Name the Core Value: Our path is novel. Lean into MVPs and be open to unexpected outcomes
Learn by doing
We'll begin training selected sites in _____ _____ of _____
First Quarter of 2023
Components of a typical trial visit.
physical _____, a _____ and ______ sample, logging the ________, and some additional________
physical exam, a blood draw and urine sample, logging the return and refill of the study drug, and some additional paperwork
It's important that we represent the company's _______________ and ________ ________.
Professionalism and Scientific Acumen
Computational Biology. Loyal is on a mission to comprehend the __________ __________ that contribute to _____. This involves computational biology to help __________, ________, and ________ the vast ___________ data required to solve the aging problem.
Computational Biology. Loyal is on a mission to comprehend the molecular mechanisms that contribute to aging. This involves computational biology to help produce, process, and analyze the vast multivariate data required to solve the aging problem.
Name the Core Value: We empower others, lead with context, and provide background information
Transparency and rejecting paternalism
TRUE/FALSE: It's ok to tell the hospital the name of the drug when answering questions about our products and trials.
FALSE. This is a very confidential part of our trials.
Objection: I DON'T HAVE EXPERIENCE WITH THIS
What are some of the tools and resources our CRA team will provide to the hospital?
Clinical Research Associates (CRAs) will train all site staff on the study protocol, conduct, and forms. CRAs are also available to provide support throughout the study which includes on-site visits to answer questions, monitor study documentation, and give additional training, as needed.