Biology
ToxLog
Drug Mechanism
Classifications
BONUS!
100

This is also known as an abnormal myeloid cell.

What is a blast?

100

This is the Latin long name for administration by mouth.


What is per os?

100

Gleevec, one of the first drugs to inhibit this type of enzyme, is used to target this mutation in CML patients

What is tyrosine kinase and BCR-ABL?

100

IPSS stands for this.

What is International Prognostic Scoring Scale?

100

This member of our office is from Hong Kong.


Who is Gabi?

200

Because of their overlapping features, these three diagnoses have been grouped into the category of Philadelphia-negative classical myeloproliferative neoplasms.


What are Polycythemia Vera, Essential Thrombosis, and Primary Myelofibrosis?

200

This two word indication can be used to resolve the following query: There is no matching AE corresponding to Ondansetron.

What is nausea prophylaxis?

200

An anti-inflammatory pre-transfusion prophylaxis is most commonly this type of steroid.

What are glucocorticoids?

200

The IPSS-R bases a risk score for MDS on 5 categories. The categories include bone marrow blast percentage, hemoglobin levels, chromosomal abnormalities, neutrophil count, and this fifth category.

What is platelet count?

200

Itzel cannot drink some alcoholic beverages, due to this allergy.


What is Fructose?

300

This is the difference between Hemoglobin and Hematocrit.


What is: Hemoglobin = protein contained in RBCs and Hematocrit= percentage of total blood that is RBCs?

300

This is the opposite of a DNR.




What is Full Code?

300

A rapidly emerging approach to cancer treatment includes uses a person’s own immune cells to treat their cancer. Most recently, the FDA approved this type of therapy for the treatment of acute lymphoblastic leukemia (ALL).


What is CAR T-cell therapy?

300

MRD is achieved when leukemic cells are no longer detected in the bone marrow but this method of residual disease assessment is more sensitive and may detect such cells.

What is flow cytometry or PCR?

300

This person is known to brag about their wilderness survival skills, which include being able to lift marginally heavy objects and eat trash out of the garbage.


Who is Caroline Andy?

400

These are the two main types of lymphocytes.

What are B cells and T cells?

400

Although we are most likely familiar with Heparin because it is used to flush out PICC lines, heparin can also be prescribed to reduce the risk of this condition.


What is a blood clot?

400

Venetoclax induces rapid onset apoptosis because of its ________ of this anti-apoptotic protein.

What is inhibition and BCL2.

400

WHO classification is divided into AML with genetic abnormalities, AML with myelodysplasia-related changes, AML not otherwise specified, Myeloid sarcoma, myeloid proliferation related to Down syndrome, mixed phenotype acute leukemia and this subtype.

What is therapy-related AML/AML related to previous chemotherapy or radiation?

400

This is what Jess’ name stands for.


What is “Jesus is real?”

500

This is the name of the active site of an antibody.


What is epitope?

500

This drug inhibits the reabsorption of sodium in the body

What is Lasik/Furosemide?

500

Grapefruits and Seville oranges are contraindicated with certain chemotherapy drugs because of the inhibition of the activity of this enzyme, which can disrupt the metabolizing of the chemotherapy in this part of the body.


What is CYP3A4 and intestine?

500

This mutation is a favorable one for AML patients according to the 2017 European Leukemia Net classification system.

What is: Mutated NPM1 without FLT3-ITD or with FLT3-ITDlow†; Biallelic mutated CEBPA

500

Spencer is known to sometimes take a break during work to walk his dog, who is a mix of these two breeds.

What are German shepherd and Corgi?