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Cells, cells, cells
Types of Leukemia
Lab findings
Anesthetic Considerations
Misc
100
A hematopoetic stem cell
What is the precursor to all blood cells in the body?
100
Has the lowest survival rate of all leukemia's.
What is AML?
100
An expected abnormal blood count with most acute leukemia's which accounts for s/s of bruising.
What is thrombocytopenia?
100
This lab value should be assessed if a patient with leukemia presents and regional anesthesia is being considered.
What is a platelet count?
100
When a person recieves his or her own stem cells for transplant.
What is Autologous transplantation?
200
A blast cell
What is an immature blood cell?
200
A translocation of chromosome 9 and 22.
What is the Philadelphia chromosome?
200
2-3% (cell count)
What is a normal Blast cell count?
200
What route of medication should be avoided in a neutropenic patient?
What is rectal route?
200
These are important to assess ina patient receiving chemotherapy.
What is CBC, lytes, renal function, and EKG?
300
Prevents mutated calls from returning.
What is Maintenance phase of Chemotherapy?
300
95% of people with this type of Leukemia have the Philadelphia chromosome.
What is CML?
300
Blast count greater than 20%
What is a blast count indicative of Leukemia?
300
This can be a intra-operative pulmonary complication in a person receiving chemotherapy.
What is a Bronchospasm?
300
These chemotherapeutic agents may cause cardiomyopathy.
What is Vincristine and Cyclophosphamide? (Anthracyclines are cardiotoxic)
400
A WBC lower than 4,000.
What is leukopenia?
400
Caused by a DNA mutation in the myeloid cells
What is AML and CML.
400
Tumor lysis syndrome causes these lab abnormalities.
What causes increased K, increased phos, and decreased Ca?
400
Your pt is on chemotherapy and you are most concerned with what heart condition that can be sub-clinical.
What is Cardiomyopathy?
500
The appearance if a bone marrow aspirate that would be indicative of leukemia.
What is a hyper-cellular bone marrow aspirate?
500
The cause of Lymphocytic Leukemia. (on the cellular level)
What is a mutation in the t-lymphoblast or a b-lymphoblast?
500
Lab value caused by a "leaking" in blast cells into blood.
What is an increase of serum leukocytes?
500
This medication commonly given to prevent PONV (and edema due to student DL abuse) can increase the risk of tumor lysis synrome.
What is Decadron? (Decadron has anti-cancer properties and should be avoided)
500
Overall survival rate of graft versus host disease.
What is 42%