Cancer
Telomeres
Interdisciplinary
Cell Cycle
100

What is a tumour suppressor gene

It is a type of  gene that makes proteins to control cell growth and keeps cell from dividing too quickly, often described as the brakes of a cell

100

What is telomerase

An enzyme complex that uses an RNA template to add telomeric repeats and maintain chromosome ends

100

What software is used to predict a protein's 3D structure from its genetic sequence?

AlphaFold

100

What is S phase

It is the phase where DNA is copied before cell division

200

What is Metastasis

It is the process by which cancer cells spread through blood or lymphatic vessels to form secondary tumours

200

What is the Hayflick Limit

The number of times a normal human cell population will divide before cell division stops 

200

What nanoemeter range does nanotech typically fall in?

1-100 nanometers

200

Is DNA replication and cell division the same thing? If no, how are they different?

Dna replication happens during the s-phase while cell division happens during the M-phase

300

What is a proto-oncogene

The gene that tells cells exacttly when to grow, mutiply and repair. This gene when mutated becomes stuck as an overactive oncogene that causes cancer

300

What is a centromere

The structure that joins two sister chromatids together at the centre of a duplicated chromosome

300

What molecules or protein chains ensure that the nanocarrier only binds to its target receptors?

Antibodies

300

If n is the number of cells that pass through the 'M' stage of the cell cycle , then what is the number of output cells in terms of n

2n

400

What is p53 and what is it's importance

It is tumour suppressor gene that is broken in almost half of all human cancers, and losing it removes the cell's ability to respond to DNA damage alarms 

400

Are chromosome and chromatid the same thing?If no, then how are they different 

Chromatid is half of a duplicated chromosome 

400

What are ionizable lipids?

Lipids that stay neutral in the blood to protect healthy, but become protonated in the endosome's acidic environment to aid in cytoplasmic escape.

400

What is the difference between Chromosome and Chromatid

Chromosome is the whole functional unit of DNA , while a chromatid is just one identical half of a duplicated chromosome

500

in terms of the stages/phases of the cell cycle how is the cell cycle of a cancer cell different to that of normal cell

Cancer cells don't enter the G0, G1 and G2 Phase and replicates rapidly during the S phase with many errors

500

What is the repeat sequence of Telomeres

TTAGGG

500

What is Polyethylene Glycol?

A polymer that when attached to the outside of a lipid sphere prevents plasma proteins from sticking to it, protecting it from the immune system.

500

What is the number of sister chromatids in a duplicated human chromosome 

92 sister chromatids (a duplicated human cell has 46 chromosomes, which means it contains a total of 92 sister chromatids