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Pharmacotherapeutics
Pharmacokinetics and...
Pharmacodynamics
Adverse Effects
Nursing Management
100
used to treat hypercholesterolemia
What is lovastatin
100
increases bioavailability of
What is NO2
100
most important fact
What is raise HDL and lower LDL
100
liver disease
What is statin contraindication
100
check these baseline values
What is liver and cholesterol
200
lovastatin decreases mortality associated with these diagnoses
What is primary and secondary CAD
200
reason for decreased oral bioavailability
What is high 1st pass effect
200
good cholesterol
What is HDL
200
very few AE
What is generally well tolerated
200
CK in danger zone
What is 10x normal
300
lovastatin is used after these two events
What is MI, stroke
300
is another reason for reduced oral bioavailability
What is highly protein bound
300
bad cholesterol
What is LDL
300
muscle weakness (aches and cramps)
What is myopathies
300
possible rhabdomyolysis
What is unexplained muscle weakness/pain and elevated CK
400
lovastatin is an adjunct therapy for
What is HTN
400
and yet another reason for reduced oral bioavailability
What is impaired absorption by food
400
range is 40-60, but not lower than 35
What is HDL
400
initially elevated for 3-12 months, maybe 3x normal
What is liver enzymes
400
look out for muscle weakness
What is myopathy
500
10% reduction in cholesterol correlates to this reduction in CHD
What is 20%-30%
500
possible drugs interactions caused by
What is p450 metabolism
500
range is <100, but not higher than 130
What is LDL
500
acute and fatal damage to skeletal muscle, with CK levels 10x normal
What is rhabdomylosis
500
stop statin treatment
What is CK is 10x normal