500
This medication should be taken at bedtime, after a low-fat snack, and doses should be individualized according to patient response. The recommended dose escalation is:
Initial Titration: weeks 1-4, 500 mg daily dose; weeks
5-8, 1000 mg daily dose; after week 8, 1500 mg daily dose-2000 mg daily dose. After week 8, titrate to patient response and tolerance. Daily dose should not be increased more than 500 mg in a 4-week period, and doses above 2000 mg daily are not recommended.
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