Experiment 1
In areas where action potentials and calcium concentration were amplified, it appears that the back-propagating action potential have become this ___________.
What is "Nonregenerative?"
Which recently discovered channels and phenomena prompted this investigation?
What are "Cation Channels in the dendrites" and "Back Propagating Action Potentials"?
𝚫F/F is a measure of _______
Change in calcium concentration
___ was used to inhibit the voltage-gated sodium channel blocker to block back-propagating action potentials
What is "TTX" ?
The amplitude in this part of a neuron does not seem to increase between unpaired and paired action potentials.
What effect did increasing inward current have on AP propagation?
What is "Enhances AP Propagation?"
Pairing _____ and _____ leads to a greater calcium increase than either on their own
What is "Subthreshold stimulation" and "APs"?
True or False: Local blockade of dendritic Na+ channels and AP back-propagation was reversible
What is "True" ?
This term is used to describe the summation of the pairing of the subthreshold EPSP and the unpaired action potentials.
What is "Supralinear?"
True or False: The enhancement of AP amplitude and Intracellular Calcium concentration by the EPSC is greater for dendrites proximal to the soma.
False
This drug blocks NMDA receptors and rhymes with “ABC”
What is "APV" ?
___ regions are most affected by the blocking of back-propagating action potentials.
What is "Distal" ?
An increase in calcium concentration during a paired EPSPs and action potential is more apparent in this area relative to the soma
What is "distal" ?
What conclusions were drawn about the effects of the EPSC on back propagating AP?
What is "modulation of potential and calcium influx in dendrites"?
What is the associative signal for Hebbian plasticity in hippocampal neurons?
What is "Action potential (back-propagation)" ?
What conditions showed a decrease in EPSP potentiation?
What is "Unpaired, TTX, hyperpolarizing" ?
What does APV stand for?
What is "(2R)-amino-5-phosphonovaleric acid" ?