NSCLC
The three subgroups of NSCLC
What is adenocarcinoma, Squamous, and Large Cell?
SCLC has a clear relationship to this social activity
What is smoking?
Most efficacious modality for treatment of NSCLC
Treatment goal for limited stage SCLC
What is cure?
Carboplatin is dosed using this equation
What is Calvert equation?
Has a clear association with smoking
What is squamous cell?
Percentage of lung cancers that are categorized as SCLC
General treatment for mutation positive NSCLC
What is targeted therapy?
SCLC is too rapidly growing to use this treatment option
What is surgery?
Nephrotoxicity and CINV are most common with this platium agent
What is Cisplatin?
Paraneoplastic syndrome associated with NSCLC
What is hypercalemia?
Places where SCLC commonly metastasizes to
What is lymph nodes, liver, adrenal glands, bone, bone marrow, and brain?
Agents that can be used in patients with PD-L1 mutation
What is Pembrolizumab, Atezolizumab, or Nivolumab?
Treatment for limited stage SCLC
Common adverse effects of taxane agents
What is edema, neutropenia, myelosuppression, alopecia, and neuropathy?
Common mutations found in adenocarcinomas
What is EGFR, KRAS, ALK, and ROS-1?
Part of the lungs that SCLC is located
What is central and peripheral regions?
Preferred treatment option for advanced disease PS 2 Squamous NSCLC
What is Carboplatin + (nab-Paclitaxel or Gemcitabine or Paclitaxel)?
Preferred treatment for extensive stage SCLC
What is combination platinum based chemotherapy without radiation?
Drug class of Pemetrexed
What is antimetabolite (anti-folate)?
Diagnosed based off of exclusion
What is Large-cell?
Define extensive stage disease
What is tumor not confined to hemithorax of origin, not contained in a radiation port, or distant metastasis?
Preferred neoadjuvant and adjuvant treatment of nonsquamous NCLC
What is Cisplatin + Pemetrexed every 21 days x 4 cycles?
Treatment for relapse/refractory
What is repeat originally regimen if relapse > 6 months or choose a new regimen if relapse < 6 months
Vinca Alkaloids should never be given through this route of administration
What is intrathecally?