SCLC
These are the two stages in SCLC
What are Limited and Extensive?
This medication should be administered with Cisplatin as first line therapy for nonsquamous NSCLC
What is Pemetrexed?
Treatment of this mutation include Erlotinib, Gefitinib, Afatinib, Osimertinib, and Dacomitinib
What is EGFR?
Patients on platinum-based agents experience this serious ADR the most
What is CINV?
This kind of therapy is recommended for Limited Stage, but not for Extensive Stage
What is Radiation?
Taxanes are part of the regimen (along with a platinum) for this stage of NSCLC
What is Squamous NSCLC?
Treatment of this mutation include Crizotinib, Ceritinib, Alectinib, Brigatinib, and Lorlatinib
What is ALK?
Patients should be given this steroid prior to starting Pemetrexed in order to minimize ADR's
What is Dexamethasone?
The backbone of the Primary Therapy for Extensive SCLC
What is Cisplatin/Carboplatin + Etoposide/Irinotecan?
The agent that is used in NSCLC when a patient who have hypersensitivity to paclitaxel or docetaxel
What is Nab-Paclitaxel?
This mutation is used to predicted TKI resistance, and patients generally have lower survival.
What is KRAS?
This route of administration should never be given with Vinorelbine
What is Intrathecally?
SCLC shows this kind of growth
What is Rapid Growth?
Patients who cannot tolerate the side effects of Cisplatin should be switched to this agent
What is Carboplatin?
Pembrolizumab should be used in the absence of these 2 mutations
What are EGFR and ALK mutations?
Common ADR's of this class of drugs include myelosuppression, neutropenia, edema, alopecia, and neuropathy as well as fluid retention and hypotension
What are Taxanes?
This therapy should be given in the presence of brain metastases.
What is Whole Brain Radiation Therapy?
Squamous NSCLC is associated most with this behavioral risk factor
What is smoking?
This PD-L1 inhibitor is indicated for Unresectable NSCLC and Extensive stage SCLC
What is Durvalumab?
QTc prolongation is a common ADR for this class of targeted therapy
What are ALK inhibitors?