What are the four layers of the trachea seen in this image? State them in order from closest to furthest from the lumen.
mucosa, submucosa, cartilage, adventitia
What is the abundant structure around the outside of the lumen that can be visualized on histology of the lobar and segmental bronchi?
lung parenchyma
Where is the last place to find smooth muscle in the airways as you move distally?
alveolar rings
What disease does this patient have?
chronic bronchitis
This JeffMD thread director is also known for his previous role at Kaplan Test Prep
Dr. Macnow
What kind of epithelium does the mucosa have?
ciliated pseudostratified columnar epithelium
Where do you first see a cuboidal epithelium in the conducting airway?
terminal bronchioles
What are the three components of the interalveolar septa?
Type I pneumocytes, type II pneumocytes, capillaries
Name a histological finding that you might seen in an asthmatic patient.
What is our class's least favorite app?
GroupMe
The specialized cells shown in this image pose what function for the trachea?
mucociliary escalator
Name one of three histological changes that can be seen in any of the four layers as you move distally into the lobar and segmental bronchi.
1. hyaline cartilage now in plates (rather than rings)
2. more prominent smooth muscle bands in submucosa
3. muscularis layer added between mucosa and submucosa
Which cell type is the most abundant in the alveoli?
type I pneumocytes
Explain the mechanism of action of the disease causing this histological finding and how it affects lung compliance.
emphysema, obstructive lung disease, high lung compliance
destruction of elastin in alveolar wall decreases elastic recoil force
What event do the admissions committee members secretly go to?
cookie hour
Name another special cell in the mucosa (other than a goblet cell) and list its function.
basal cells (in basal lamina): proliferative
brush cells: communicate with afferent nerve endings
Kulchitsky cells: neuroendocrine cells
What two features seen in upper airway structures are lost in non-respiratory bronchioles?
submucosa, hyaline cartilage plates (goblet cells also acceptable)
What are the abundant cells in the airway lumen?
alveolar macrophages
A biopsy of this patient's lung may be positive for what cell type & what symptoms may a patient with this disease present with?
bronchiectasis, neutrophils, severe cough with foul-smelling bloody sputum, worse in the morning
What is that one random food associated with G6PD deficiency?
FAVA BEANS
What connects the ends of cartilage in the trachea?
trachealis muscle (smooth muscle)
Where are these cuboidal cells found and what are their three functions?
terminal bronchioles
1. detoxify 2. produce surfactant 3. proliferative
What are the structures that connect individual alveolar sacs?
What composes the mucus plugs found on histology in an asthmatic patient?
How many times does Dr. Majdan say history in his favorite phrase "history history history?"
one too many