Day 3
Lymphocytes that go to the thymus to mature
Immunological Memory doesn't occur with what type of immunity?
Passive Immunity
Cytotoxic Cells or Killer T Cell release what toxic chemicals?
perforins and granzymes
The most common type of allergies?
Immediate Hypersensitivity
What are the two types of body defense systems? Describe them.
Innate - nonspecific; responds to all foreign particles
Adaptive - very specific; responds to one particular foreign particle
What are the 3 aspects of adaptive defenses?
1) antigen specific
2) Has memory
3) Its systemic
The 4 ways antibodies inactivate antigens.
1) Complement Fixation
2) Neutralization
3) Agglutination
4) Percipitation
The 4 different types of grafts
1) Autografts
2) Isografts
3) Allografts
4) Xenografts
It occurs when the allergen directly enters the blood and circulates rapidly through the body
Name 5 types of leukocytes
1) Neutrophils
2) Eosinophils
3) Basophils
4) Lymphocytes
5) Monocytes
being able to respond to a specific antigen by binding to a antigen specific receptor
What are Antibodies?
Soluble proteins secreted by activated B-Cells or by plasma in response to an antigen
What is antigen presentation essential for?
Essential for activation and clonal function of T-Cells
Histamine is responsible for what during allergies?
Small blood vessels dilating and leaky and many symptoms ppl recognize like runny nose, watery eyes, and itching.
What is it called when WBCs multiply and increase by a lot due to an infection in the body.
Leukocytosis
What are 2 major lymphocytes and what do they do?
B Cells - produce antibodies
T- Cells - deals with cellular mediated arms/fights other cells directly
Difference between 1st Humoral Response and Secondary Humoral Response
Secondary Humoral Response are produced faster, more prolonged, and more effective than the 1st.
Why is Immunosuppressive Therapy given and what is its downside?
Describe Autoimmune Disease
The immune system loses the ability to tolerate self antigens while still recognizing and attacking foreign antigens so the body prod antibodies that attack and damage its own tissues.
1st attacks intact membranes and their secretions
2nd is nonspecific and will attack whatever no matter the foreign invader
What is the 3rd line of defense?
A functional system that recognizes foreign molecules and acts to inactivate or destroy them?
Active: B cells encounter antigens and produces antibodies against them.
Passive: Antibodies are obtained through a serum of a immune human
Describe how Regulatory T Cells play a role in cell mediated immunity?
They stop immune response after the antigen has been inactivated or destroyed
Delayed hypersensitivities are mediated by what subgroup of helper T-Cells ?
Cytotoxic T Cells and macrophages
What does MALT stand for and what is its purpose?
1) Mucosa Associated Lymphoid Tissue; protects the respiratory and digestive tracts from foreign objects