Interstitial fluid that has entered the lymphatic system
Skin and mucous membranes are physical components of this
First line of defense
This type of leukocyte is part of the adaptive (specific) immune response
Lymphocyte
Antibody involved in the allergic response
IgE
Extensively vascular organ that helps filter blood through areas of red and white pulp; lacks a strong outer capsule
Spleen
Also called terminal lymphatics, these vessels are one cell layer thick
Lymphatic capillaries
Cells (NKs, phagocytes), antimicrobial substances (interferons, cytokines), and internal processes (inflammation, fever) are part of this line of defense
Second line of defense
This type of lymphocyte matures in the bone marrow
B-lymphocyte (B-cell)
Helps activate B cells
IgD
There are approximately 500-600 of these encapsulated nodules of lymphoid and reticular tissue scattered throughout the body
Lymph nodes
Similar in structure to veins, lymphatic vessels also contain these structures, to prevent the regurgitation or "back flow" of lymph
Valves
These cells induce apoptosis in abnormal or infected cells by secreting perforins and granzymes
Natural Killer Cells
Type of T-lymphocyte that kills infected cells and releases immune stimulating chemicals
Cytotoxic t-cells
First antibody on the scene during the primary immune response
IgM
Effective against inhaled pathogens, these lymphoid nodules found along bronchi and between the bronchi and arteries
BALT (bronchus associated lymphoid tissue)
This duct drains all regions of the body except for the right half of the head, neck, chest, abdomen, and the right upper extremity
Thoracic duct
These four types of leukocytes are part of the innate (nonspecific) immune response
Neutrophils, eosinophils, basophils, monocytes
Type of B-cell that produces antibodies
Plasma cell
Main antibody of the secondary immune response; can be passed to the developing fetus through the placenta
IgG
Type of immunity gained when a person is administered immunoglobulins harvested from another person or animal
Passive, artificial, acquired immunity
Vessels where the right lymphatic and the thoracic ducts empty
Right and left subclavian veins
Cause of vasodilation and increased capillary permeability leading to edema (swelling) during the inflammatory response
Histamine
Type of B cell that is a long living immune cell reserved for future exposure to a pathogen
Memory cell
Secretory immunoglobulin that is on surface of mucous membranes and can be passed to an infant through breastmilk
IgA
Also known as the pharyngeal tonsil, this patch of lymphoid tissue is effective against inhaled and ingested pathogens
Adenoid