500
What is the significance of Lennox's description of the events of the night before he and Macduff arrive at Inverness? "The night has been unruly. Where we lay, Our chimneys were blown down, and as they say, Lamentings heard i' th' air, strange screams of death, And prophesying with accents terrible, Of dire combustion, and confused events, New hatched to th' woeful time."
What is that something has disrupted the order of the world?