Medications
What is the medication used to treat Malignant Hyperthermia?
Dantrolene
What are the first signs of an MH Crisis?
Unexplained tachycardia or PVC's and increased End Tidal CO2
What is MH?
What is a potentially fatal inherited disorder. It is a biochemical chain reaction response, triggered by commonly used anesthetic gases and paralyzing agents, within the skeletal muscles of susceptible individuals.
What is the hotline to call when you identify an MH Crisis?
MHAUS
What is Dantrolene reconstituted with?
Preservative Free Sterile Water
What is the first thing the circulator does when an MH crisis is noticed?
Call 711 and call for extra help
What are triggering agents?
Anesthetic gases (Halothane, Isoflurane, Enflurane, Sevoflurane, Desflurane) and Succinylcholine
Where is the MHAUS number located?
on the MH Cart
How much sterile water do you reconstitute each Dantrolene vial with?
60 mL
The first thing anesthesia does when an MH crisis is identified?
Stop triggering agents (gases and succinylcholine) and hyperventilate with 100% Oxygen
Pediatric Patients
The account for 52% of cases occurring
What are ways to cool your patient?
Ice packs, cool irrigation, cold IV saline, cooling blankets
What is the dosage and route of Dantrolene?
2.5mg/kg IV
What are other signs of impending MH Crisis?
Masseter muscle rigidity and increased body temperature
What is the gold standard for MH testing?
DAILY DOUBLE
A Muscle Biopsy - The Caffeine Halothane Contracture Test
Where is ice located?
In preop and pacu
How frequently you give Dantrolene?
Repeat as needed until symptoms decrease
Where do you pack a patient with ice to cool them?
When can MH Crisis occur?
Quickly after triggering agents are given
Fun Fact: or within 1 hr up to 72 hrs post exposure
Where does the patient go after an MH Crisis?
Admit the patient to PACU or ICU for close monitoring post crisis