Basics
This is a life-threatening reaction to certain anesthesia agents
What is malignant hyperthermia
This inhaled anesthetic class commonly triggers MH
What are volatile anesthetics
This is often the earliest sign of MH during surgery
What is an increased end-tidal CO2?
This is the antidote for MH
What is Dantrolene or Ryanodex?
MH involves uncontrolled release of this ion in muscle tissue
What is calcium?
MH is inherited in this pattern
Autosomal Dominant
This paralytic agent is a well-known MH trigger
What is Succinylcholine
This muscle symptom is a hallmark sign
What is muscle rigidity?
First step after recognizing MH in the OR
What is discontinue triggering agents?
The Organelle stores calcium in muscle cells
What is the sarcoplasmic reticulum?
This gene is most commonly associated with MH
What is RYR1
These anesthetics are considered safe and do NOT trigger MH
What are non-triggering agents (e.g., propofol, local anesthetics)
This vital sign change occurs later in MH
What is hyperthermia?
This supportive measure helps reduce body temperature
What is active cooling?
Excess calcium leads to this metabolic state.
What is hypermetabolism?
This test confirms susceptibility to MH using muscle tissue
What is the caffeine-halothane contracture test
This situation can increase suspicion even without anesthesia exposure.
What is exertional heat illness
This dangerous electrolyte imbalance can lead to arrhythmias.
What is Hyperkalemia?
This intervention helps correct acidosis
What is administering bicarbonate?
This process causes heat production
What is muscle contraction?
This population is most at risk if there is a family history.
Who are surgical patients receiving general anesthesia
Name two triggers of MH
What are volatile anesthetics and succinylcholine
This dark urine finding indicates muscle breakdown
What is myoglobinuria?
This organization provides MH treatment guidelines and hotline support
What is MHAUS (Malignant Hyperthermia Association of the United States?
MH can occur intraoperatively or in this postoperative timeframe
What is early postoperative period?