Patho
This life threatening condition is a hypermetabolic reaction of skeletal muscle triggered by certain anesthetics.
What is malignant hyperthermia
This change in body temperature occurs late and can rise above 110 degrees.
What is hyperthermia?
True or False: A patient with prior uneventful anesthesia is not at risk for MH
What is false
The first person anesthesia staff should notify when MH is suspected.
Who is the attending anesthesiologist?
Where are the MH carts located?
Outside of OR 9/16??
In the PACU by bay 14, next to the crash cart.
In MH, too much of this mineral is released inside muscle cells.
What is Calcium
These states have a higher incidence of Malignant Hyperthermia. (name at least one of four)
-Nebraska
-Michigan
-Wisconsin
-West Virginia
This depolarizing muscle relaxant is a known MH trigger.
What is succinylcholine?
This is the first step when MH is suspected.
What is discontinue triggering agents?
This newer formulation of dantrolene requires less dilution.
What is muscle break down (rhabdomyolysis)
Dark brown urine in MH is caused by this condition
What is myoglobinuria
the presence of the oxygen binding muscle protein myoglobin in the urine, resulting from severe muscle damage (rhabdo)
True or False: MH can only affect adult patients.
This type of IV fluid is used to help lower a patient’s body temperature.
What is cold saline?
This medication helps treat metabolic acidosis
What is sodium bicarbonate?
What vital sign changes would you expect to see in a patient with MH?
Tachycardia, Tachypnea
This is often the earliest detectable sign of MH during surgery.
What is increasing ETCO2
This type of history may suggest MH susceptibility even before surgery.
What is family history of unexplained death during anesthesia? Family or personal history of complications with anesthesia.
Cooling should stop once temperature drops below this Celsius value.
What is 38°C?
Name 3 medications found in the Malignant Hyperthermia Kit and where are these found?
Found in pyxis located in: OR-A, ParmaOR and BV Anes
This system in muscle cells becomes dysregulated in MH, causing excessive calcium release.
What is the sarcoplasmic reticulum
This mixed acid-base disturbance is seen in MH.
What is metabolic and respiratory acidosis
Name one inhaled anesthetic agent that can trigger MH.
What is sevoflurane / isoflurane / desflurane / halothane / enflurane
Name one external cooling method.
What is applying ice packs?
What is the dosing of ryanodex?
What is 2.5mg/kg