Arcade
NES
Sega Genesis
SNES
Portables
100

Before becoming household names, this hero and his teammates starred in this Data East 4 player Beat Em' Up who's final boss is the Red Skull

What is Captain America and The Avengers

100

This released by LJN Games final Stage could only be accessed inputting a password that was printed on the cartridge label, The Final Boss is Magneto

What is Uncanny X-Men (Will accept X-Men)

100

Sega Released this game in 1991 staring this Amazing Hero as he looks for the keys that can deactivate the bomb placed by his enemy the Kingpin in the city of New York.

What is Spider-Man vs. The Kingpin (Will accept just Spider-Man since I remember the box only saying Spider-Man)

100

This game released by capcom starring this merry band of Mutants has as the Final Boss Magneto, even when the tittle suggests that the final boss is this Egyptian despot.

What is X-Men: Mutant Apocalypse 

100

This Game for the Game Gear is the first in a Trilogy of Games about this mutants.

What is X-Men

200

This Beat em' Up released by sega starring your friendly neighborhood web slinger and 3 other not that well related heroes has as the Final Boss The Kingpin 

What is Spider-Man The Video Game

200

This released by LJN Game stars this most famous Canadian hero, Magneto is not the Final Boss but he is a level boss, the Final boss is the protagonist arch-rival Sabretooth.

What is Wolverine.

200

This game starring the merry band of Mutants has as the Final Boss Magneto, it's famous for its Reset gimmick that makes it unfinishable if played on the Nomad.

What is X-Men.

200

This Seudo sequel to X-Men: Mutant Apocalypse adapts freely the Infinity Gauntlet storyline years before the MCU movies.

Whats is Marvel Super Heroes in War of the Gems

200

The Sequel to the game from the Portables 100 answer, This game released just one year after the original Game Gear Game.

What is X-Men: Gamesmaster's Legacy

300

This Beat em' Up starring the Avenging vigilante Frank Castle and his ally Nick Fury has as the Final Boss The Kingpin 

What is the Punisher

300

This released by LJN Game has its protagonist face a sextet of the protagonist greatest foes.

What is Spider-Man: Return of the Sinister Six

300

This game starring the merry band of Mutants has Magneto as a playable character for the first time, before Anakin complained about the sand this copys of the protagonist striked first.

What is X-Men 2: Clone Wars

300

This released by LJN Game stars this most famous Canadian hero, the soundtrack composed by Shahid Ahmad and Dylan Beale is notable for its resemblance to grime music possibly even before the inception of the genre.

What is Wolverine: Adamantium Rage

300

The Sequel to the sequel from the Portables 100 answer, This game released just one year after the sequel to the original Game Gear Game came out.

What is X-Men: Mojo World

400

This Fighting Game Starring the merry band of Mutants has as the Final Boss Magneto who tells you play time is over.

What is X-Men Children of the Atom.

400

This released by LJN Shooter starring the Avenging vigilante Frank Castle has him battle classic foes like Jigsaw and a Tank???

The Punisher

400

This released by LJN Games stars not only the spectacular web-head but also this group of men (and woman), who try to escape the murderworld of this title character's deadly theme park.

What is Spider-Man and the X-Men in Arcade's Revenge

400

This game staring Spider-Man is based on the animated series airing on FOX at the time.

What is Spider-Man (Yes this game is really just called Spider-Man, maybe The Animated Series would have been a better subtitle)

400

This Game is everything but _________, but hey the comic is called that, nobody would buy the Mediocre Spider-man, Incredible this game was developed by RARE

What is The Amazing Spider-Man

500

This 6 player game starring the merry band of Mutants has as the Final Boss Magneto the Master of Magnet.

What is X-Men the Arcade Game

500

This Not released by LJN Game was distributed by Arcadia Systems and stars the shiny herald of Galactus in a mission to frustrate even the AVGN, at least the Music is awesome.

What is Silver Surfer

500

This released by LJN Game staring Spider-Man follows the story of this famous 90's storyline, The Cartridge is also known for being red.

What is Spider-Man and Venom: Maximum Carnage (Will Accept Maximum Carnage)

500

This game staring Spider-Man never came to the US a real shame considering what did come out.

What is The Amazing Spider-Man: Lethal Foes

500

The Sequel to the Portables 400, not really that much  imagination guys.

What isThe Amazing Spider-Man 2