Induction Medications
This agent binds to GABAa and increases chloride conductance which results in hyperpolarization of post-synaptic cell membrane and inhibition of post-synaptic neuron.
What is propofol?
could be etomidate or benzos too
The MAC of this inhaled anesthetic is 0.75
What is Halothane?
This new drug on the market is a mixture of phenylephrine and ephedrine.
What is phenylphedrine?
This NMBD lacks vagolytic properties and is stored as a powder due to its instability in a solution.
What is vecuronium?
Once atropine has been proven unsuccessful, this agent is used for overdose of beta blockers. Dose?
What is glucagon at 1-10mg IV
If a patient comes into the OR with an infusion of esmolol at a rate of 250 mcg/kg/min, what adjustments will you make with your induction drugs?
How do you decrease your propofol dose?
A patient with a history of seizures should avoid this agent.
What is enflurane?
This drug causes direct beta stimulation and indirect alpha stimulation through release of endogenous norepinephrine.
What is ephedrine?
Patient with TOF 1 twitch needs reversal with sugammdex.
How much is 4 mg/kg?
This muscle is most commonly monitored intraoperatively because it is one of the last to recover from paralysis
What is adductor pollicis?
Benzodiazepines have little effect on CV system normally, except under this specific condition which will cause profound hypotension.
What is hypovolemia?
Inhaled agent that decreases SVR and BP the least.
What is sevoflurane?
The effects of norepi and epinephrine on coronary arteries.
What is vasodilation?
vasoconstriction in all other vascular beds**
Factors that can potentiate NMBDs (4)
What is hypothermia, hypermagnesemia, large doses of LA, antidysrhythmics (quinidine)?
These receptors limit production of Ach and protect against bronchoconstriction.
What are M2 receptors?
Onset: <30 seconds
Peak: 3.6 minutes
Duration: 30-60 minutes (IV)
What is fentanyl?
The MAC with 60-70% N2O of this agent is 0.50.
What is isoflurane?
The antiemetic dose of ephedrine.
How much is 0.5 mg/kg IM?
Intubating dose of vecuronium
How much is 0.08 - 0.1 mg/kg
These receptors are responsible for bronchoconstriction and mucus plug.
What are M1 and M3 receptors?
Onset: 60-90 sec
Peak: 1-3 min
Duration: 20-50 min
excreted in bile
What is rocuronium?
the concentration of anesthetics that prevents consciousness in 50% of people but will respond appropriately.
What is MAC-awake?
Onset immediate
peak: 1 minute
duration: 15-20 minutes
bolus dose of 50-200 mcg
What is phenylephrine?
How long is 86 minutes?
A purely chemical process that results in loss of the positive charges by molecular fragmentation to laudanosine (tertiary amine) and a monoquaternary acrylate.
What is Hoffman Elimination?