The Dark Side of Pathophysiology
Cardiology: Responsible for circulation every parsec of your life
Jedi Mind Tricks / Neurology
Alien Invasions - Infectious Disease
Space Medicine
100
Electrolyte abnormality most commonly associated with peaked T waves on ECG
Hyperkalemia
100
Heart sound associated with rapid ventricular filling, may be heard in heart failure
S3
100
Cranial nerve responsible for eye movement
Cranial nerve III or oculomotor
100
Bacterium most commonly responsible for community-acquired pneumonia (name genus and species)
Streptococcus pneumoniae
100
Metabolic disorder experienced by astronauts due to prolonged microgravity
Osteoporosis or bone demineralization
200
Autoimmune disease characterized by antibodies against acetylcholine receptors causing muscle weakness, or "loss of the force", with a decremental response during repetitive nerve stimulation
Myasthenia gravis
General Myasthenia Greivous
200
Chest pain relieved by leaning forward, diffuse ST elevations
Pericarditis
200
Neurologic condition caused by dopamine deficiency in the substantia nigra
Parkinson disease
200
Virus causing infectious mononucleosis
Epstein-Barr virus
200
What happens to plasma volume during prolonged exposure to microgravity?
Plasma volume decreases
300
Vasculitis commonly associated with anti-proteinase-3 antibodies
Granulomatosis with polyangiitis
300
In the RALES trial this medicine showed a significant reduction in the primary outcome of all-cause mortality in patients with CHF NYHA III-IV and EF<35%
Spironolactone
300
If the Death Star were a lipoprotein, the presence of this apolipoprotein side chain would indicate that the Death Star is actually a genetically inherited lipid particle that is strongly associated with increased ischemic stroke risk.
Apo(a), will accept lipoprotein a
300
Fungal infection is classically associated with broad-based budding yeast
Blastomycosis
300
This dangerous condition occurs when nitrogen bubbles form in the bloodstream due to rapid altitude changes without proper pressurization
Decompression sickness
400
Metabolic condition that leads to fruity breath due to ketone production
DKA
400
The three beta-blockers showing mortality benefit in HfrEF
Bisoprolol, carvedilol, and metoprolol succinate
400
What nerve roots are tested by the brachioradialis reflex
C5-C6
C6 Protocol Droid
400
Organism that causes gas gangrene through alpha toxin production (hint: common foodborne pathogen that can be found in milk and dairy products)
Clostridium perfringens
400
This U.S. agency conducts human spaceflight research to understand how microgravity affects the body
NASA
500
Type of hypersensitivity reaction is responsible for serum sickness
Type III hypersensitivity
500
This landmark trial established the superiority of sacubitril/valsartan over enalapril, showing a 20% RRR and 4.7% ARR in CV mortality and hospitalization due to heart failure
PARADIGM-HF
500
PE finding of facial muscles that differentiates Bell's Palsy from a CVA mediated central palsy.
Sparing of forehead muscles in CVA, forehead muscles affected in Bell's Palsy
500
Acute, self-limited, febrile illness occurring in the first 24 hours of treatment of spirochetal infections
Jarisch-Herxheimer reaction (accept Herxheimer)
500
A commercial space craft depressurizes over the eastern seaboard and safely lands in the Camden Clark patient parking lot, and comes to a stop in front of the North Tower drop-off. The passengers have joint pain, headaches, shortness of breath, and neurologic changes. In addition to giving 100% O2 and IVFs, what definitive treatment can we offer at Camden Clark AND where do we offer it?
Hyperbaric Oxygen Treatment, MOB-A (wound care center)