INFLAMMATORY BOWEL DISEASE
What is the most common extraintestinal manifestation of Ulcerative Colitis?
Arthritis/ arthropathy
Name the preferred serological test ordered as part of diagnostic workup for Celiac Disease
IgA anti-tissue transglutaminase (anti-tTG) antibodies
Iron deficiency anemia, cervical esophageal web and dysphagia
Plummer-Vinson or Paterson-Brown-Kelly syndrome
Name a parasite that causes pancreatitis
Toxoplasma, Ascaris and cryptopsporidium
What factors are included in the Maddrey discriminant function score for disease severity and mortality risk assessment in patients with alcoholic hepatitis?
Prothrombin time and bilirubin
What test is associated with the development of inflammatory bowel disease-related enteropathic spondyloarthritis in patients with axial or type I peripheral arthritis?
HLA B27
Name 2 syndromes considered high risk groups for Celiac Disease
Down's and Turner's syndrome
Dysphagia to solids that is only gradually progressive
Esophageal stricture
What is the serum triglyceride level required for HTG to be considered the underlying etiology of acute pancreatitis?
500 mg/dl
One of 2 autoantibodies characteristic of type 2 autoimmune hepatitis.
Antibodies to LKM-1 alone or accompanied by anti-liver cytosol antibody-1 (ALC-1).
What is the induction therapy for mild to moderate ulcerative proctitis?
Rectal mesalamine (suppository or enema)
What test is ordered for patients with histologic findings suggestive of celiac disease (eg, villous atrophy) but negative serologies?
We perform HLA-DQ2/DQ8 genotyping.
This class of antibiotics is most implicated in causing pill esophagitis
Tetracyclines
How are patients with acute pancreatitis in the intensive care unit monitored for potential abdominal compartment syndrome?
Serial urinary bladder pressure measurements
(>20mmHG)
What are the 2 indications for urgent phlebotomy in hemachromatosis?
End organ damage
Ferritin more than 1000 ng/ml
What blood test should be monitored closely being treated with 5-ASA for induction therapy for left sided or extensive UC?
Serum creatinine
In a patient with selective IgA deficiency, what is the best serological test for the diagnosis of celiac disease?
IgG-based testing with deamidated gliadin peptide (DGP) IgG.
An Adult with history of asthma, eczema, food allergies complains of Solid food dysphagia and food impactions.
Eosinophilic esophagitis
A Ranson criteria score greater than this number is associated with 100% mortality.
7
Name any one of the preferred treatment regimens for chronic Hepatitis C
glecaprevir/pibrentasvir
ledipasvir/sofosbuvir
elbasvir/grazoprevir
sofosbuvir/velpatasvir
The thiopurines exert a glucocorticoid-sparing effect for patients with IBD who cannot maintain remission when glucocorticoids are tapered or withdrawn. What blood test should be ordered before starting the drug?
TPMT enzyme activity with phenotype testing
Name the extraintestinal manifestation of Celiac Disease which affects the CNS
Non hereditary cerebellar ataxia
Botulinum toxin therapy can be considered in patients who are not good candidates for more definitive therapy with pneumatic dilation or surgical myotomy. Botulinum toxin is injected into the LES and increases LES smooth muscle tone by poisoning the neurons that release this chemical substance.
Acetylcholine
What rare but serious complication of acute pancreatitis should be suspected when patients with acute pancreatitis have unexplained gastrointestinal bleeding, an unexplained drop in hematocrit, or sudden expansion of a pancreatic fluid collection?
Pseudoaneurysm
Kayser-Fleischer rings are brownish rings that are due to fine, pigmented, granular deposits of copper in Descemet's membrane in the cornea, Name another ocular manifestation of Wilsons disease.
Sunflower cataract (copper deposition in the lens)