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What is Antidepressant discontinuation syndrome? (ADDS ) 

a set of physical and psychological symptoms that can happen when you suddenly stop or quickly reduce your antidepressant medication

Manifestations: Difficulty sleeping, anxiety, depression, and flu-like symptoms.  Insomnia, nausea, imbalance, sensory disturbances, and hyperarousal.



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what is serotonin syndrome?

- High influx of serotonin 

Manifestations •Restlessness •Sweating •Dilated pupils •Tachycardia and blood pressure •Muscle rigidity and loss of muscle coordination.

Mental status changes • Confusion • Anxiety • Hallucinations • Difficulty concentrating • Restlessness • Tremors • Hyperpyrexia • Ataxia • Abdominal pain • Fluctuating/labile blood pressure


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What is anticholinergic Syndrome 

Symptoms-  Red as a beet: skin beet red and hot to the touch.   Mad as a hatter: staring, restless, purposeless.   Dry as a bone: dry skin, dry mouth, intense thirst.  Difficulty speaking and swallowing.   Memory impairment 

Treatment:Induce vomiting,Physostigmine (Antilirium) , Reversal of CNS effects caused by overdose of drugs capable of causing anticholinergic syndrome, administered IV