Types of Skin Cancer
skin cancer that starts in melanocytes
What is melanoma?
the biggest environmental risk factor for skin cancer
What is UV radiation from the sun?
What is limiting UV exposure (e.g. sunscreen)
cellular process that usually kills damaged cells before a cancer forms
What is apoptosis?
current research goal in melanoma treatment
What is developing personalized and specific therapies?
the most common but least deadly skin cancer
What is basal cell carcinoma?
people with this trait have higher risk for skin cancer
What is light skin?
What is a biopsy?
genes that inhibit tumor formation
What are tumor suppressor genes?
why combination therapy is preferred over single agent targeted therapy
What is it reduces resistance and improves effectiveness
skin cancer that arises from keratinocytes and has a higher metastatic risk
What is squamous cell carcinoma?
a history of this increases melanoma risk
What are severe sunburns?
reason size alone is an unreliable melanoma indicator
What is that melanomas can be small but still aggressive
What is oncogenes promote cell division while tumor suppressors stop cell division?
What is surgical excision?
skin cancer most strongly linked to intermittent, intense UV exposure
What is melanoma?
population trend observed in melanoma incidence recently
What is increasing incidence, especially among young adults.
a measure of melanoma thickness
What is Breslow depth?
gene mutation commonly driving uncontrolled cell growth in melanoma
What is a BRAF mutation?
mechanism that improves melanoma survival rates
What is blocking immune checkpoints to enhance T-cell response?
reason basal cell carcinoma rarely metastasizes
What is Xeroderma pigmentosum?
What is PET or CT scanning?
type of mutation caused by UV light that stops DNA polymerase
What is BRAF
limitation of immunotherapy in melanoma treatment
What is not all patients respond and immune related side effects?