Post-polio syndrome, muscle pain, spasm, and meningeal inflammation if nervous tissue is infected but not destroy, infection of motor neuron can lead to deformed limbs, flaccid paralysis, and loss of reflex
What is Polio?
100
Mucosal cells in oropharynx and intestine via receptor mediated endocytosis; poliovirus receptor: PVR and CD 155 - glycosylated membrane protein
What is Polio?
100
mRNA is synthesized by RDRP while being encapsulated with capsid protein. The 11 mRNA are then translated into structural and nonstructural protein
What is Rotavirus
100
Aseptic meningitis, skin rash, herpangina, and conjunctivitis
What is Coxsackie A
100
Disinfect and avoid contact
What is Coronaviridae
200
Common cold virus with more than 100 serotypes, Can't replicate in GI tract due to gastric acid, can lead to secondary bacterial infection
What is Rhino?
200
Replicate in the upper respiratory tract and multiplies in epithelium of salivary ducts and could spread via bloodstream
What is Mumps (Rubulavirus)?
200
Transcribes of 8 genome segments into 8 mRNA in the nucleus
What is Influenza?
200
Aseptic meningitis, paralysis, upper respiratory tract infection, myocarditis, fever, rash, GI and cold-like infection
What is Echovirus
200
Supportive care: pain, artificial ventilation for respiratory failure, physical therapy/ IPV (inactivated) and OPV (attenuated)
What is Polio
300
Most common disease causing enterovirus, known as the Hand-Foot-and-Mouth disease, Herpangina, highly infectious
What is Coxsackie A?
300
Initially it infects upper respiratory epithelial cells, but can spread lymph nodes and spleen as well. Attachment via hemagglutinin and penetration and uncoating occur simultaneously
What is Measles (Morbillivirus)?
300
Synthesis of the plus strand (mRNA) from the minus strand
What is Measles (Morbillivirus)
300
Headache, chills, fatigue, sore throat, cough, and nasal discharge (yellow green mucous by secondary bacteria infection)
What is Rhino
300
No effective treatment/ MMR vaccine (attenuated) which covers measles, mumps, and rubella. A booster is recommended
What is Measles (Morbillivirus)
400
Most common disease causing enterovirus, upper respiratory tract infection, spinal cord infection can lead to paralysis
What is Coxsackie B?
400
Infects upper respiratory tract: enter via nose and eye and replicate in nasopharynx
What is Respiratory syncytial virus (RSV) (Pneumovirus)?
400
From RNA to DNA. Integration of DNA into host genome, from DNA to mRNA to protein