The Lymph System
A colorless liquid similar to blood plasma
What is Lymph
This type of antigen includes PAMPs such as components of microbial cell walls, flagella, and pili.
What are Exogenous Antigens
This type of lymphocytes originates and matures in this primary lymphatic organ.
What is red bone marrow
These originate in red bone marrow but mature in a different primary lymphatic organ called the
What is the thymus
MHC stands for
Major Histocompatibility Complex
What is the heart
This type of antigen is derived from normal human cell cellular processes. Lymphocytes which are sensitive to this type of antigen should experience clonal deletion before reaching maturation.
What are Autoantigens
Antigen-sensing sites on the B-cell membrane are called this
What are B-Cell Receptors
T-cells target these kinds of infections/ pathologies specifically
What are cells which present abnormal antigens on MHC class I proteins
MHC Class I is found on the surface of all . . .
What are nucleated human cells. (What is an example of a human cell that does not have a nucleus?)
Primary Lymphoid Organs include. . .
What are Red Bone Marrow and the Thymus
This type of antigen is found on the surface of infected human cells.
What are Endogenous Antigens
When an extracellular pathogen has activated its corresponding b-cell, that lymphocyte turns into an antibody-secreting plasma cell. The resulting free antibodies coat the pathogen to aid in phagocytosis by a different cell. This is called
Opsonization
Abnormal MHC I antigens can arise from
What are infected or cancerous cells. Abnormal antigens on MHC I can come from cancer cells or from human cells suffering from an intracellular infection.
MHC class II are found only on the surface of . . .
What are antigen presenting cells (APCs).
What is an example of an APC?
Secondary Lymphoid Organs include . . .
In organ transplantation, the similarity of the donor's and recipients ____________ must be ensured to avoid rejection of the organ.
What are autoantigens
When a BCR is no longer attached to the surface of a B-cell, it is called . . .
What is an Antibody or a Free Immunoglobulin
A very few self-recognizing T-cells (cells which react to autoantigens) survive and mature to become this type of T-cell.
What are Regulatory T-Cells
In a healthy cell, MHC class I displays only this kind of antigen
What are human autoantigens
Lymph is highly concentrated with these types of cells.
What are B-cell and T-cell Lymphocytes
Blood Connective Tissue can easily be transfused between people, even with vastly different immune systems, because erythrocytes lack this antigen.
What are autoantigens displayed on MHC Class I
When a unique B-cell encounters the epitope it is specific to, it immediately undergoes division and becomes this type of cell
What is an immunoglobulin secreting plasma cell
Cytotoxic T-cells directly kill infected or cancerous cells by
What is a Cell-Mediated Immune Response involving the release of poisonous (cytotoxic) chemicals
A dendritic cell feels a flagellum slide by and quickly phagocytizes the invader. After 'digesting' the pathogen, foreign fragments are displayed on . . .
What is MHC Class II